New briarane diterpenoids from the gorgonian coral Junceella juncea

Jiun Yang Chang; Chia Ching Liaw; Ahmed Eid Fazary; Tsong Long Hwang; Ya Ching Shen

doi:10.3390/md10061321

New briarane diterpenoids from the gorgonian coral Junceella juncea

Jiun Yang Chang, Chia Ching Liaw, Ahmed Eid Fazary, Tsong Long Hwang, Ya Ching Shen^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

22 Scopus citations

Abstract

Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.

Original language	English
Pages (from-to)	1321-1330
Number of pages	10
Journal	Marine Drugs
Volume	10
Issue number	6
DOIs	https://doi.org/10.3390/md10061321
State	Published - 06 2012

Keywords

Anti-inflammatory activity
Briaranes
Junceella juncea

Access to Document

10.3390/md10061321

Cite this

@article{55ec39f621204d9583ebadf9bfef0001,

title = "New briarane diterpenoids from the gorgonian coral Junceella juncea",

abstract = "Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.",

keywords = "Anti-inflammatory activity, Briaranes, Junceella juncea",

author = "Chang, {Jiun Yang} and Liaw, {Chia Ching} and Fazary, {Ahmed Eid} and Hwang, {Tsong Long} and Shen, {Ya Ching}",

year = "2012",

month = jun,

doi = "10.3390/md10061321",

language = "英语",

volume = "10",

pages = "1321--1330",

journal = "Marine Drugs",

issn = "1660-3397",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "6",

}

TY - JOUR

T1 - New briarane diterpenoids from the gorgonian coral Junceella juncea

AU - Chang, Jiun Yang

AU - Liaw, Chia Ching

AU - Fazary, Ahmed Eid

AU - Hwang, Tsong Long

AU - Shen, Ya Ching

PY - 2012/6

Y1 - 2012/6

N2 - Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.

AB - Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.

KW - Anti-inflammatory activity

KW - Briaranes

KW - Junceella juncea

UR - http://www.scopus.com/inward/record.url?scp=84863425848&partnerID=8YFLogxK

U2 - 10.3390/md10061321

DO - 10.3390/md10061321

M3 - 文章

C2 - 22822375

AN - SCOPUS:84863425848

SN - 1660-3397

VL - 10

SP - 1321

EP - 1330

JO - Marine Drugs

JF - Marine Drugs

IS - 6

ER -

New briarane diterpenoids from the gorgonian coral Junceella juncea

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this