New furanocembranoids from briareum violaceum

Pin Chang Huang, Wen Sou Lin, Bo Rong Peng, Yu Chia Chang, Lee Shing Fang, Guo Qiang Li, Tsong Long Hwang, Zhi Hong Wen, Ping Jyun Sung*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

8 Scopus citations

Abstract

Three new furanocembranoids-briaviodiol F (1) and briaviotriols A (2) and B (3)-along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1-3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides.

Original languageEnglish
Article number214
JournalMarine Drugs
Volume17
Issue number4
DOIs
StatePublished - 2019

Bibliographical note

Publisher Copyright:
© 2019 by the authors.

Keywords

  • Anti-inflammatory
  • Briareum violaceum
  • Briaviodiol
  • Briaviotriol
  • Inos

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