Abstract
Three new furanocembranoids-briaviodiol F (1) and briaviotriols A (2) and B (3)-along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1-3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides.
Original language | English |
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Article number | 214 |
Journal | Marine Drugs |
Volume | 17 |
Issue number | 4 |
DOIs | |
State | Published - 2019 |
Bibliographical note
Publisher Copyright:© 2019 by the authors.
Keywords
- Anti-inflammatory
- Briareum violaceum
- Briaviodiol
- Briaviotriol
- Inos