New furanocembranoids from briareum violaceum

  • Pin Chang Huang
  • , Wen Sou Lin
  • , Bo Rong Peng
  • , Yu Chia Chang
  • , Lee Shing Fang
  • , Guo Qiang Li
  • , Tsong Long Hwang
  • , Zhi Hong Wen
  • , Ping Jyun Sung*
  • *Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

8 Scopus citations

Abstract

Three new furanocembranoids-briaviodiol F (1) and briaviotriols A (2) and B (3)-along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1-3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides.

Original languageEnglish
Article number214
JournalMarine Drugs
Volume17
Issue number4
DOIs
StatePublished - 2019

Bibliographical note

Publisher Copyright:
© 2019 by the authors.

Keywords

  • Anti-inflammatory
  • Briareum violaceum
  • Briaviodiol
  • Briaviotriol
  • Inos

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