New hydroperoxybriarane diterpenoids from the octocoral Briareum violaceum

Jia Wen Yao; Wei Chiung Chi; Jing Hao Xu; Gene Hsiang Lee; Michael Y. Chiang; Bo Rong Peng; Nai Cheng Lin; Chiung Chin Hu; Lee Shing Fang; Guo Qiang Li; Yu Chia Chang; Tsong Long Hwang; Ping Jyun Sung

doi:10.1016/j.tet.2019.01.069

New hydroperoxybriarane diterpenoids from the octocoral Briareum violaceum

Jia Wen Yao
, Wei Chiung Chi
, Jing Hao Xu
, Gene Hsiang Lee
, Michael Y. Chiang
, Bo Rong Peng
, Nai Cheng Lin
, Chiung Chin Hu
, Lee Shing Fang
, Guo Qiang Li
, Yu Chia Chang
, Tsong Long Hwang
, Ping Jyun Sung^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

6 Scopus citations

Abstract

A known briarane, brianthein W (1), along with four new hydroperoxybriaranes, briaviolides R–U (2–5), have been obtained from the octocoral Briareum violaceum. The absolute configuration of 1 was determined by X-ray analysis for the first time and the structures of briaranes 2–5 were established by spectroscopic methods. Bioactivity study showed that briarane 3 decreased the production of superoxide anions from human neutrophils.

Original language	English
Pages (from-to)	1510-1516
Number of pages	7
Journal	Tetrahedron
Volume	75
Issue number	11
DOIs	https://doi.org/10.1016/j.tet.2019.01.069
State	Published - 15 03 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Ltd

Keywords

Brianthein W
Briareum violaceum
Briaviolide
Superoxide anion

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10.1016/j.tet.2019.01.069

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title = "New hydroperoxybriarane diterpenoids from the octocoral Briareum violaceum",

abstract = "A known briarane, brianthein W (1), along with four new hydroperoxybriaranes, briaviolides R–U (2–5), have been obtained from the octocoral Briareum violaceum. The absolute configuration of 1 was determined by X-ray analysis for the first time and the structures of briaranes 2–5 were established by spectroscopic methods. Bioactivity study showed that briarane 3 decreased the production of superoxide anions from human neutrophils.",

keywords = "Brianthein W, Briareum violaceum, Briaviolide, Superoxide anion",

author = "Yao, \{Jia Wen\} and Chi, \{Wei Chiung\} and Xu, \{Jing Hao\} and Lee, \{Gene Hsiang\} and Chiang, \{Michael Y.\} and Peng, \{Bo Rong\} and Lin, \{Nai Cheng\} and Hu, \{Chiung Chin\} and Fang, \{Lee Shing\} and Li, \{Guo Qiang\} and Chang, \{Yu Chia\} and Hwang, \{Tsong Long\} and Sung, \{Ping Jyun\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = mar,

day = "15",

doi = "10.1016/j.tet.2019.01.069",

language = "英语",

volume = "75",

pages = "1510--1516",

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TY - JOUR

T1 - New hydroperoxybriarane diterpenoids from the octocoral Briareum violaceum

AU - Yao, Jia Wen

AU - Chi, Wei Chiung

AU - Xu, Jing Hao

AU - Lee, Gene Hsiang

AU - Chiang, Michael Y.

AU - Peng, Bo Rong

AU - Lin, Nai Cheng

AU - Hu, Chiung Chin

AU - Fang, Lee Shing

AU - Li, Guo Qiang

AU - Chang, Yu Chia

AU - Hwang, Tsong Long

AU - Sung, Ping Jyun

PY - 2019/3/15

Y1 - 2019/3/15

N2 - A known briarane, brianthein W (1), along with four new hydroperoxybriaranes, briaviolides R–U (2–5), have been obtained from the octocoral Briareum violaceum. The absolute configuration of 1 was determined by X-ray analysis for the first time and the structures of briaranes 2–5 were established by spectroscopic methods. Bioactivity study showed that briarane 3 decreased the production of superoxide anions from human neutrophils.

AB - A known briarane, brianthein W (1), along with four new hydroperoxybriaranes, briaviolides R–U (2–5), have been obtained from the octocoral Briareum violaceum. The absolute configuration of 1 was determined by X-ray analysis for the first time and the structures of briaranes 2–5 were established by spectroscopic methods. Bioactivity study showed that briarane 3 decreased the production of superoxide anions from human neutrophils.

KW - Brianthein W

KW - Briareum violaceum

KW - Briaviolide

KW - Superoxide anion

UR - https://www.scopus.com/pages/publications/85060988572

U2 - 10.1016/j.tet.2019.01.069

DO - 10.1016/j.tet.2019.01.069

M3 - 文章

AN - SCOPUS:85060988572

SN - 0040-4020

VL - 75

SP - 1510

EP - 1516

JO - Tetrahedron

JF - Tetrahedron

IS - 11

ER -

New hydroperoxybriarane diterpenoids from the octocoral Briareum violaceum

Abstract

Bibliographical note

Keywords

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