New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

Tsong Long Hwang; Mei Ru Lin; Wei Tse Tsai; Hsiao Chien Yeh; Wan Ping Hu; Jyh Horng Sheu; Ping Jyun Sung

doi:10.1246/bcsj.81.1638

New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

Tsong Long Hwang, Mei Ru Lin, Wei Tse Tsai, Hsiao Chien Yeh, Wan Ping Hu, Jyh Horng Sheu, Ping Jyun Sung^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

29 Scopus citations

Abstract

Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

Original language	English
Pages (from-to)	1638-1646
Number of pages	9
Journal	Bulletin of the Chemical Society of Japan
Volume	81
Issue number	12
DOIs	https://doi.org/10.1246/bcsj.81.1638
State	Published - 2008

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title = "New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta",

abstract = "Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.",

author = "Hwang, {Tsong Long} and Lin, {Mei Ru} and Tsai, {Wei Tse} and Yeh, {Hsiao Chien} and Hu, {Wan Ping} and Sheu, {Jyh Horng} and Sung, {Ping Jyun}",

year = "2008",

doi = "10.1246/bcsj.81.1638",

language = "英语",

volume = "81",

pages = "1638--1646",

journal = "Bulletin of the Chemical Society of Japan",

issn = "0009-2673",

publisher = "Chemical Society of Japan",

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TY - JOUR

T1 - New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

AU - Hwang, Tsong Long

AU - Lin, Mei Ru

AU - Tsai, Wei Tse

AU - Yeh, Hsiao Chien

AU - Hu, Wan Ping

AU - Sheu, Jyh Horng

AU - Sung, Ping Jyun

PY - 2008

Y1 - 2008

N2 - Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

AB - Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

UR - http://www.scopus.com/inward/record.url?scp=58149307955&partnerID=8YFLogxK

U2 - 10.1246/bcsj.81.1638

DO - 10.1246/bcsj.81.1638

M3 - 文章

AN - SCOPUS:58149307955

SN - 0009-2673

VL - 81

SP - 1638

EP - 1646

JO - Bulletin of the Chemical Society of Japan

JF - Bulletin of the Chemical Society of Japan

IS - 12

ER -

New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

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