New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

Tsong Long Hwang; Mei Ru Lin; Wei Tse Tsai; Hsiao Chien Yeh; Wan Ping Hu; Jyh Horng Sheu; Ping Jyun Sung

doi:10.1246/bcsj.81.1638

New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

Tsong Long Hwang
, Mei Ru Lin
, Wei Tse Tsai
, Hsiao Chien Yeh
, Wan Ping Hu
, Jyh Horng Sheu
, Ping Jyun Sung^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

National Museum of Marine Biology and Aquarium, Taiwan
National Sun Yat-sen University
National Dong Hwa University
Kaohsiung Medical University

Research output: Contribution to journal › Journal Article › peer-review

31 Scopus citations

Abstract

Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

Original language	English
Pages (from-to)	1638-1646
Number of pages	9
Journal	Bulletin of the Chemical Society of Japan
Volume	81
Issue number	12
DOIs	https://doi.org/10.1246/bcsj.81.1638
State	Published - 2008

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title = "New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta",

abstract = "Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.",

author = "Hwang, \{Tsong Long\} and Lin, \{Mei Ru\} and Tsai, \{Wei Tse\} and Yeh, \{Hsiao Chien\} and Hu, \{Wan Ping\} and Sheu, \{Jyh Horng\} and Sung, \{Ping Jyun\}",

year = "2008",

doi = "10.1246/bcsj.81.1638",

language = "英语",

volume = "81",

pages = "1638--1646",

journal = "Bulletin of the Chemical Society of Japan",

issn = "0009-2673",

publisher = "Oxford University Press",

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TY - JOUR

T1 - New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

AU - Hwang, Tsong Long

AU - Lin, Mei Ru

AU - Tsai, Wei Tse

AU - Yeh, Hsiao Chien

AU - Hu, Wan Ping

AU - Sheu, Jyh Horng

AU - Sung, Ping Jyun

PY - 2008

Y1 - 2008

N2 - Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

AB - Six new polyoxygenated briarane-type diterpenoids, briaexcavatins Q-T (1-4) and robustolides J (5) and K (6), were isolated from a cultured octocoral Briareum excavation and a sea whip gorgonian coral Ellisella robusta, respectively. The structures of briaranes 1-6 were established by spectroscopic methods. Briarane 3 exhibited weak cytotoxicity toward CCRF-CEM tumor cells and briaranes 5 and 6 displayed inhibitory effects on superoxide anion generation by human neutrophils.

UR - https://www.scopus.com/pages/publications/58149307955

U2 - 10.1246/bcsj.81.1638

DO - 10.1246/bcsj.81.1638

M3 - 文章

AN - SCOPUS:58149307955

SN - 0009-2673

VL - 81

SP - 1638

EP - 1646

JO - Bulletin of the Chemical Society of Japan

JF - Bulletin of the Chemical Society of Japan

IS - 12

ER -

New polyoxygenated briaranes from octocorals briareum excavatum and ellisella robusta

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