No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer disease

Ying Jay Liou; Chen Jee Hong; Hsiu Chih Liu; Chia Yih Liu; Tsung Yun Liu; I. Chun Chen; Shih Jen Tsai

doi:10.1002/ajmg.10670

No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer disease

Ying Jay Liou
, Chen Jee Hong
, Hsiu Chih Liu
, Chia Yih Liu
, Tsung Yun Liu
, I. Chun Chen
, Shih Jen Tsai^*

^*Corresponding author for this work

School of Medicine

Yu-Li Veterans Hospital
Veterans General Hospital-Taipei
National Yang Ming Chiao Tung University

Research output: Contribution to journal › Journal Article › peer-review

16 Scopus citations

Abstract

Nitric oxide synthase (NOS) has been implicated in the pathogenesis of Alzheimer disease (AD). To examine the role of the neuronal NOS (nNOS) gene in AD, patients (n = 139) and control subjects (n = 101) were genotyped for the nNOS dinucleotide polymorphism. No association was demonstrated for AD and this particular nNOS polymorphism.

Original language	English
Pages (from-to)	687-688
Number of pages	2
Journal	American Journal of Medical Genetics - Neuropsychiatric Genetics
Volume	114
Issue number	6
DOIs	https://doi.org/10.1002/ajmg.10670
State	Published - 08 08 2002

Keywords

Alzheimer disease
Association
Neuronal nitric oxide synthase
Polymorphism

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10.1002/ajmg.10670

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title = "No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer disease",

abstract = "Nitric oxide synthase (NOS) has been implicated in the pathogenesis of Alzheimer disease (AD). To examine the role of the neuronal NOS (nNOS) gene in AD, patients (n = 139) and control subjects (n = 101) were genotyped for the nNOS dinucleotide polymorphism. No association was demonstrated for AD and this particular nNOS polymorphism.",

keywords = "Alzheimer disease, Association, Neuronal nitric oxide synthase, Polymorphism",

author = "Liou, \{Ying Jay\} and Hong, \{Chen Jee\} and Liu, \{Hsiu Chih\} and Liu, \{Chia Yih\} and Liu, \{Tsung Yun\} and Chen, \{I. Chun\} and Tsai, \{Shih Jen\}",

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T1 - No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer disease

AU - Liou, Ying Jay

AU - Hong, Chen Jee

AU - Liu, Hsiu Chih

AU - Liu, Chia Yih

AU - Liu, Tsung Yun

AU - Chen, I. Chun

AU - Tsai, Shih Jen

PY - 2002/8/8

Y1 - 2002/8/8

N2 - Nitric oxide synthase (NOS) has been implicated in the pathogenesis of Alzheimer disease (AD). To examine the role of the neuronal NOS (nNOS) gene in AD, patients (n = 139) and control subjects (n = 101) were genotyped for the nNOS dinucleotide polymorphism. No association was demonstrated for AD and this particular nNOS polymorphism.

AB - Nitric oxide synthase (NOS) has been implicated in the pathogenesis of Alzheimer disease (AD). To examine the role of the neuronal NOS (nNOS) gene in AD, patients (n = 139) and control subjects (n = 101) were genotyped for the nNOS dinucleotide polymorphism. No association was demonstrated for AD and this particular nNOS polymorphism.

KW - Alzheimer disease

KW - Association

KW - Neuronal nitric oxide synthase

KW - Polymorphism

UR - https://www.scopus.com/pages/publications/0037043842

U2 - 10.1002/ajmg.10670

DO - 10.1002/ajmg.10670

M3 - 文章

C2 - 12210288

AN - SCOPUS:0037043842

SN - 1552-4841

VL - 114

SP - 687

EP - 688

JO - American Journal of Medical Genetics - Neuropsychiatric Genetics

JF - American Journal of Medical Genetics - Neuropsychiatric Genetics

IS - 6

ER -

No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer disease

Abstract

Keywords

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