Abstract
Molecular epidemiologic studies have indicated the possible existence of mixed infection of different hepatitis B virus (HBV) genotypes in chronic hepatitis B (CH-B) carriers, but the effect of dual HBV genotype B and C infection on the efficacy of lamivudine therapy remains unclear. We report four CH-B patients with dual HBV genotype B and C infection and acute exacerbation who received lamivudine monotherapy for about 18 months. None of them had achieved a sustained response at the end of the 18-month trial of treatment.
Original language | English |
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Pages (from-to) | 588-593 |
Number of pages | 6 |
Journal | Journal of the Formosan Medical Association |
Volume | 105 |
Issue number | 7 |
DOIs | |
State | Published - 07 2006 |
Externally published | Yes |
Keywords
- Acute exacerbation
- Chronic hepatitis B
- Dual genotype infection
- Hepatitis B virus
- Lamivudine therapy
- Sustained response