Obstructive jaundice as the presenting manifestation of Burkitt's lymphoma in a 4-year-old boy

Chi Feng Hsu, Sheung Fat Ko, Chih Cheng Hsiao, Chie Song Shieh, Chao Cheng Huang, Fu Cheng Huang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

7 Scopus citations

Abstract

Obstructive jaundice often occurs as a late manifestation of non-Hodgkin's lymphoma (NHL), but has rarely been reported as a presenting manifestation, especially in children. We report a case of a 4-year-old-boy with Burkitt's lymphoma (small non-cleaved cell NHL) who presented with obstructive jaundice, resulting from encasement of the common bile duct by the tumor. The patient underwent near-total excision of the tumor and biliary-enteric bypass to relieve the jaundice. Combined chemotherapy was not given because of refusal by his family. Two weeks after the operation, obstructive jaundice reappeared due to a large recurrent tumor compressing the liver hilum. He recieved chemotherapy and the jaundice disappeared within 6 days. Follow-up computed tomography 1 year later revealed total resolution of the tumor. Three conclusion are suggested by this case. First, although NHL presenting as obstructive jaundice is uncommon in children, it should be included in the differential diagnosis. Second, relief of obstructive jaundice can be effective accomplished by chemotherapy alone. Third, chemotherapy should be given once NHL is diagnosed.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalJournal of the Formosan Medical Association
Volume102
Issue number2
StatePublished - 01 02 2003
Externally publishedYes

Keywords

  • Adjuvant
  • Burkitt lymphoma
  • Chemotherapy
  • Cholestasis
  • Lymphoma
  • Non-Hodgkin

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