On-treatment predictors of hepatocellular carcinoma in patients with chronic hepatitis B.

Research output: Contribution to journalJournal Article peer-review

Abstract

We read with interest the article by Ahn et al in Liver International. This study evaluated the predictive performance of various parameters at treatment baseline and 12 months of treatment with entecavir or tenofovir disoproxil fumarate for hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB) through logistic regression and machine-learning methods, and demonstrated that the logistic lasso regression algorithm using cirrhosis at baseline and alpha-fetoprotein (AFP) level and platelet count at 12 months of treatment exhibited the best performance compared with several extant HCC risk scores.
Original languageAmerican English
JournalLiver International
Volume41
Issue number7
DOIs
StatePublished - 2021

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