One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

Ya Na Chen; Po Cheng Chen; Chia Wei Wang; Yu Shen Lin; Chung Mao Ou; Lin Chen Ho; Huan Tsung Chang

doi:10.1039/c4cc03949a

One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

Ya Na Chen, Po Cheng Chen, Chia Wei Wang, Yu Shen Lin, Chung Mao Ou, Lin Chen Ho, Huan Tsung Chang^*

^*Corresponding author for this work

National Taiwan University

Research output: Contribution to journal › Journal Article › peer-review

77 Scopus citations

Abstract

A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I₄₁₀/I₆₅₀) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.

Original language	English
Pages (from-to)	8571-8574
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	62
DOIs	https://doi.org/10.1039/c4cc03949a
State	Published - 08 07 2014
Externally published	Yes

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abstract = "A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I410/I650) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.",

author = "Chen, {Ya Na} and Chen, {Po Cheng} and Wang, {Chia Wei} and Lin, {Yu Shen} and Ou, {Chung Mao} and Ho, {Lin Chen} and Chang, {Huan Tsung}",

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AU - Chen, Ya Na

AU - Chen, Po Cheng

AU - Wang, Chia Wei

AU - Lin, Yu Shen

AU - Ou, Chung Mao

AU - Ho, Lin Chen

AU - Chang, Huan Tsung

PY - 2014/7/8

Y1 - 2014/7/8

N2 - A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I410/I650) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.

AB - A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I410/I650) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.

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U2 - 10.1039/c4cc03949a

DO - 10.1039/c4cc03949a

M3 - 文章

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JO - Chemical Communications

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ER -

One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

Abstract

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