One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

Ya Na Chen; Po Cheng Chen; Chia Wei Wang; Yu Shen Lin; Chung Mao Ou; Lin Chen Ho; Huan Tsung Chang

doi:10.1039/c4cc03949a

One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

Ya Na Chen
, Po Cheng Chen
, Chia Wei Wang
, Yu Shen Lin
, Chung Mao Ou
, Lin Chen Ho
, Huan Tsung Chang^*

^*Corresponding author for this work

National Taiwan University

Research output: Contribution to journal › Journal Article › peer-review

79 Scopus citations

Abstract

A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I₄₁₀/I₆₅₀) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.

Original language	English
Pages (from-to)	8571-8574
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	62
DOIs	https://doi.org/10.1039/c4cc03949a
State	Published - 08 07 2014
Externally published	Yes

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title = "One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes",

abstract = "A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I410/I650) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.",

author = "Chen, \{Ya Na\} and Chen, \{Po Cheng\} and Wang, \{Chia Wei\} and Lin, \{Yu Shen\} and Ou, \{Chung Mao\} and Ho, \{Lin Chen\} and Chang, \{Huan Tsung\}",

year = "2014",

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doi = "10.1039/c4cc03949a",

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T1 - One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

AU - Chen, Ya Na

AU - Chen, Po Cheng

AU - Wang, Chia Wei

AU - Lin, Yu Shen

AU - Ou, Chung Mao

AU - Ho, Lin Chen

AU - Chang, Huan Tsung

PY - 2014/7/8

Y1 - 2014/7/8

N2 - A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I410/I650) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.

AB - A facile, one-pot synthetic approach has been developed for the preparation of BSA–Ce/Au NCs. The fluorescence intensities of BSA–Ce/Au NCs at 410 and 650 nm are pH dependent and independent, respectively. The fluorescence intensity ratio (I410/I650) is linear against pH values from 6.0 to 9.0. These stable and biocompatible BSA–Ce/Au NCs have been used as ratiometric probes for monitoring local pH values inside HeLa cells.

UR - https://www.scopus.com/pages/publications/84904123427

U2 - 10.1039/c4cc03949a

DO - 10.1039/c4cc03949a

M3 - 文章

AN - SCOPUS:84904123427

SN - 1359-7345

VL - 50

SP - 8571

EP - 8574

JO - Chemical Communications

JF - Chemical Communications

IS - 62

ER -

One-pot synthesis of fluorescent BSA–Ce/Au nanoclusters as ratiometric pH probes

Abstract

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