Oscillatory pallidal local field potential activity correlates with involuntary EMG in dystonia

C. C. Chen; A. A. Kühn; K. T. Hoffmann; A. Kupsch; G. H. Schneider; T. Trottenberg; J. K. Krauss; J. C. Wöhrle; E. Bardinet; J. Yelnik; P. Brown

doi:10.1212/01.wnl.0000196470.00165.7d

Oscillatory pallidal local field potential activity correlates with involuntary EMG in dystonia

C. C. Chen
, A. A. Kühn
, K. T. Hoffmann
, A. Kupsch
, G. H. Schneider
, T. Trottenberg
, J. K. Krauss
, J. C. Wöhrle
, E. Bardinet
, J. Yelnik
, P. Brown^*

^*Corresponding author for this work

School of Medicine

Research output: Contribution to journal › Journal Article › peer-review

93 Scopus citations

Abstract

The pathophysiology of dystonia is unclear. The authors recorded local field potentials (LFPs) from deep brain stimulation electrodes implanted in the pallidum of 13 dystonic patients. LFP power correlated with the level of dystonic EMG in the sternocleidomastoid, with maximal positive correlations at the lower contacts of pallidal electrodes. The data suggest that the neuronal synchronization indexed by LFP oscillations in the globus pallidus may be mechanistically linked to dystonic EMG activity.

Original language	English
Pages (from-to)	418-420
Number of pages	3
Journal	Neurology
Volume	66
Issue number	3
DOIs	https://doi.org/10.1212/01.wnl.0000196470.00165.7d
State	Published - 02 2006

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10.1212/01.wnl.0000196470.00165.7d

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@article{7cea556322bd4833b9ae7562e20566e2,

title = "Oscillatory pallidal local field potential activity correlates with involuntary EMG in dystonia",

abstract = "The pathophysiology of dystonia is unclear. The authors recorded local field potentials (LFPs) from deep brain stimulation electrodes implanted in the pallidum of 13 dystonic patients. LFP power correlated with the level of dystonic EMG in the sternocleidomastoid, with maximal positive correlations at the lower contacts of pallidal electrodes. The data suggest that the neuronal synchronization indexed by LFP oscillations in the globus pallidus may be mechanistically linked to dystonic EMG activity.",

author = "Chen, \{C. C.\} and K{\"u}hn, \{A. A.\} and Hoffmann, \{K. T.\} and A. Kupsch and Schneider, \{G. H.\} and T. Trottenberg and Krauss, \{J. K.\} and W{\"o}hrle, \{J. C.\} and E. Bardinet and J. Yelnik and P. Brown",

year = "2006",

month = feb,

doi = "10.1212/01.wnl.0000196470.00165.7d",

language = "英语",

volume = "66",

pages = "418--420",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

number = "3",

}

TY - JOUR

T1 - Oscillatory pallidal local field potential activity correlates with involuntary EMG in dystonia

AU - Chen, C. C.

AU - Kühn, A. A.

AU - Hoffmann, K. T.

AU - Kupsch, A.

AU - Schneider, G. H.

AU - Trottenberg, T.

AU - Krauss, J. K.

AU - Wöhrle, J. C.

AU - Bardinet, E.

AU - Yelnik, J.

AU - Brown, P.

PY - 2006/2

Y1 - 2006/2

N2 - The pathophysiology of dystonia is unclear. The authors recorded local field potentials (LFPs) from deep brain stimulation electrodes implanted in the pallidum of 13 dystonic patients. LFP power correlated with the level of dystonic EMG in the sternocleidomastoid, with maximal positive correlations at the lower contacts of pallidal electrodes. The data suggest that the neuronal synchronization indexed by LFP oscillations in the globus pallidus may be mechanistically linked to dystonic EMG activity.

AB - The pathophysiology of dystonia is unclear. The authors recorded local field potentials (LFPs) from deep brain stimulation electrodes implanted in the pallidum of 13 dystonic patients. LFP power correlated with the level of dystonic EMG in the sternocleidomastoid, with maximal positive correlations at the lower contacts of pallidal electrodes. The data suggest that the neuronal synchronization indexed by LFP oscillations in the globus pallidus may be mechanistically linked to dystonic EMG activity.

UR - https://www.scopus.com/pages/publications/33646191848

U2 - 10.1212/01.wnl.0000196470.00165.7d

DO - 10.1212/01.wnl.0000196470.00165.7d

M3 - 文章

C2 - 16476944

AN - SCOPUS:33646191848

SN - 0028-3878

VL - 66

SP - 418

EP - 420

JO - Neurology

JF - Neurology

IS - 3

ER -

Oscillatory pallidal local field potential activity correlates with involuntary EMG in dystonia

Abstract

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