Outcomes of 75 patients over 12 years treated for acoustic neuromas with linear accelerator-based radiosurgery

Peng Wei Hsu, Cheng Nen Chang, Shih Tseng Lee, Yin Cheng Huang, Hsien Chih Chen, Chun Chieh Wang, Yung Hsin Hsu, Chen Kan Tseng, Yao Liang Chen, Kuo Cheng Wei*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

30 Scopus citations

Abstract

The aim of this study was to investigate the efficacy of linear accelerator (LINAC)-based radiosurgery in the treatment of acoustic neuromas. In this retrospective study, we enrolled 75 patients with non-neurofibromatosis type 2 acoustic neuromas who were followed-up for more than 5 years. The 75 patients were divided into 3 groups: patients with a newly diagnosed tumor; those with a residual tumor; and those with a recurrent tumor. The average follow-up period was 97.8 months. The overall tumor progression-free rate was 92%, and corresponding rates among those with newly diagnosed tumors was 100%, residual tumors was 84.4%, and recurrent tumors was 92.8% (p = 0.028). Lesion localization using CT scans correlated with a higher tendency for tumor progression than lesion localization using CT-MRI fusion images (15.6% versus 2.4%, respectively). Residual tumors treated with radiosurgery have a higher progression rate, and careful lesion localization using CT-MRI image fusion is required.

Original languageEnglish
Pages (from-to)556-560
Number of pages5
JournalJournal of Clinical Neuroscience
Volume17
Issue number5
DOIs
StatePublished - 05 2010

Keywords

  • Acoustic neuroma
  • CT
  • Gamma knife
  • Image fusion
  • LINAC
  • MRI
  • Radiosurgery

Fingerprint

Dive into the research topics of 'Outcomes of 75 patients over 12 years treated for acoustic neuromas with linear accelerator-based radiosurgery'. Together they form a unique fingerprint.

Cite this