Outcomes of fat injection laryngoplasty in unilateral vocal cord paralysis

Tuan Jen Fang, Hsueh Yu Li, Richard E. Gliklich, Ya Hui Chen, Pa Chun Wang*, Hsiu Feng Chuang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

39 Scopus citations

Abstract

Objective: To analyze outcomes following fat injection laryngoplasty in patients with unilateral vocal cord paralysis. Design: Longitudinal outcomes evaluation study. Setting: Tertiary referral voice center. Patients: Thirty-three consecutive patients with unilateral vocal cord paralysis undergoing autologous fat injection laryngoplasty with preoperative and serial postoperative follow-up at Chang Gung Memorial Hospital, Taipei, Taiwan. Intervention: Autologous fat injection laryngoplasty. Main Outcome Measures: Voice laboratory measurements, Voice Outcome Survey, and 36-item Short Form Health Survey. Results: Except for the physical functioning dimension of global health, voice-related subjective outcomes and acoustic variables of the patients significantly improved after surgery (P<.05). Compared with population norms, the mean (SD) scores of patients were inferior on the 36-item Short Form Health Survey dimensions of physical functioning (80.7 [22.3] vs 90.2 [17.4]) and role functioning-physical problems (65.0 [36.2] vs 80.2 [36.2]). Overall, 88.9% (24 of 27) of the patients were satisfied with their surgery. Conclusions: Fat injection laryngoplasty seems to be effective in enhancing acoustic and quality of life outcomes in patients with unilateral vocal cord paralysis. The effect is sustainable over 12 months.

Original languageEnglish
Pages (from-to)457-462
Number of pages6
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume136
Issue number5
DOIs
StatePublished - 05 2010

Keywords

  • AUTOLOGOUS FAT
  • FOLD PARALYSIS
  • LARYNGEAL NERVE PARALYSIS
  • MEDIALIZATION
  • TERM-FOLLOW-UP
  • VALIDATION

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