Ovarian hyperstimulation syndrome with minimal ascites and massive pleural effusion: Report of a case

M. J. Hsieh*, T. C.Y. Tsao, P. J. Cheng

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

18 Scopus citations


A 30-year-old woman was admitted to the hospital due to bilateral massive pleural effusion and right lung collapse with severe respiratory distress. She had been undergoing gamete intrafallopian transfer (GIFT) following three years of primary infertility. Ovarian stimulation was done with pure follicle stimulating hormone (FSH) and human menopausal gonadotropin (hMG) under pituitary suppression with leuprolide acetate. Bilateral chest pain and progressive dyspnea occurred six days after preovulatory oocytes with washed motile sperms were transferred laparoscopically to the fallopian tubes. Chest radiography, sonography and computed tomography revealed a massive right pleural effusion with right lung collapse, and a mild left pleural effusion. Abdominal sonography revealed minimal ascites. Supportive therapy including fluid supply and albumin infusion failed to improve the respiratory distress. A tube thoracostomy was performed, resulting in rapid reexpansion of the lung. The respiratory distress improved markedly after drainage of 6,800 mL of pleural effusion over 7 days. Massive serosanguineous pleural effusion with minimal ascites is unusual in ovarian hyperstimulation syndrome (OHSS). Tube thoracostomy is a safe and effective treatment for massive pleural effusion and lung collapse in the case of OHSS.

Original languageEnglish
Pages (from-to)882-884
Number of pages3
JournalJournal of the Formosan Medical Association
Issue number10
StatePublished - 1994
Externally publishedYes


  • ascites
  • ovarian hyperstimulation
  • pleural effusion
  • tube thoracostomy


Dive into the research topics of 'Ovarian hyperstimulation syndrome with minimal ascites and massive pleural effusion: Report of a case'. Together they form a unique fingerprint.

Cite this