Paired surface plasma waves biosensor using degree of coherence

Chien Wa Ho, Sheng Yi Chang, Nai Chuan Chen, Ying Feng Chang, Chien Chou

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Degree of coherence (DOC) of a paired surface plasma waves (PSPWs) in the paired surface plasma waves biosensor (PSPWB) is proposed and discussed in which a paired of surface plasma waves are excited by using a pair of highly spatial and temporal correlated P-polarized waves in a SPR device of the Kretschmann configuration. The heterodyne signal from reflected paired P-polarized laser beam is generated where the visibility of the signal is proportional to DOC of PSPWs in term of the ratio of AC and DC components of the signal. The experimental result shows that the DOC of PSPWs versus incident angle of laser beam which relates to intrinsic phonon distribution in metal film becomes much sensitive than conventional amplitude or intensity sensitive surface plasmon resonance (SPR) biosensor. Finally, the dynamic range of protein-protein interaction at ultralow concentrations is discussed.

Original languageEnglish
Title of host publicationPlasmonics in Biology and Medicine X
DOIs
StatePublished - 2013
EventPlasmonics in Biology and Medicine X - San Francisco, CA, United States
Duration: 03 02 201304 02 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8597
ISSN (Print)1605-7422

Conference

ConferencePlasmonics in Biology and Medicine X
Country/TerritoryUnited States
CitySan Francisco, CA
Period03/02/1304/02/13

Keywords

  • Paired SPWs
  • biosensor
  • degree of coherence
  • heterodyne interference
  • visibility

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