TY - JOUR
T1 - Pancreaticoduodenectomy versus Frey's procedure for chronic pancreatitis
T2 - Preliminary data on outcome and pancreatic function
AU - Chiang, Kun Chun
AU - Yeh, Chun Nan
AU - Hsu, Jun Te
AU - Chen, Han Ming
AU - Chen, Huang Yang
AU - Hwang, Tsann Long
AU - Jan, Yi Yin
AU - Chen, Miin Fu
PY - 2007/11
Y1 - 2007/11
N2 - Purpose. Several surgical treatments have been proposed for treating chronic pancreatitis (CP), including standard pancreaticoduodenectomy (PD), pylorus-preserving PD, Beger's procedure, and Frey's procedure; however, few studies have compared pre- and postoperative pancreatic function in patients undergoing surgery for CP. Methods. Between 1996 and 2003, 42 patients with CP underwent pancreatic head resection; as PD in 17 and as Frey's procedure in 25. Frey's procedure was chosen if the pancreatic duct was dilated more than 5mm. We conducted this prospective, nonrandomized study to compare the pre- and postoperative status after PD or Frey's procedure by evaluating pancreatic function and symptom relief. Results. The demographic features, surgical morbidity, and mortality were similar in the two groups. Pancreatic exocrine function improved, pain subsided, and complications of the adjacent organs resolved after surgery in both groups. Similar postoperative endocrine and exocrine functional results were observed in both groups. Frey's procedure was associated with a significantly shorter hospital stay than PD (10.6 versus 15.4 days, respectively; (P < 0.0001)). Conclusion. There were no significant difference in operative time, surgical morbidity, or mortality rates between PD and Frey's procedure. Both procedures were equally effective in terms of pain relief, improvement of pancreatic exocrine function, and control of complications affecting the adjacent organs; however, Frey's procedure was associated with a significantly shorter hospital stay.
AB - Purpose. Several surgical treatments have been proposed for treating chronic pancreatitis (CP), including standard pancreaticoduodenectomy (PD), pylorus-preserving PD, Beger's procedure, and Frey's procedure; however, few studies have compared pre- and postoperative pancreatic function in patients undergoing surgery for CP. Methods. Between 1996 and 2003, 42 patients with CP underwent pancreatic head resection; as PD in 17 and as Frey's procedure in 25. Frey's procedure was chosen if the pancreatic duct was dilated more than 5mm. We conducted this prospective, nonrandomized study to compare the pre- and postoperative status after PD or Frey's procedure by evaluating pancreatic function and symptom relief. Results. The demographic features, surgical morbidity, and mortality were similar in the two groups. Pancreatic exocrine function improved, pain subsided, and complications of the adjacent organs resolved after surgery in both groups. Similar postoperative endocrine and exocrine functional results were observed in both groups. Frey's procedure was associated with a significantly shorter hospital stay than PD (10.6 versus 15.4 days, respectively; (P < 0.0001)). Conclusion. There were no significant difference in operative time, surgical morbidity, or mortality rates between PD and Frey's procedure. Both procedures were equally effective in terms of pain relief, improvement of pancreatic exocrine function, and control of complications affecting the adjacent organs; however, Frey's procedure was associated with a significantly shorter hospital stay.
KW - Chronic pancreatitis
KW - Frey's procedure
KW - Pancreaticoduodenectomy
UR - http://www.scopus.com/inward/record.url?scp=35448981495&partnerID=8YFLogxK
U2 - 10.1007/s00595-007-3539-z
DO - 10.1007/s00595-007-3539-z
M3 - 文章
C2 - 17952526
AN - SCOPUS:35448981495
SN - 0941-1291
VL - 37
SP - 961
EP - 966
JO - Surgery Today
JF - Surgery Today
IS - 11
ER -