Abstract
We report two cases of intrathoracic Castleman disease presenting with paraneoplastic syndrome. Patient 1 was a 10-year-old girl with short stature. She was found to have delayed bone age, slow growth velocity, and iron-deficiency anemia, which was refractory to treatment. Thrombocytosis and hypergammaglobulinemia were later detected. Chest X-ray revealed a hilar mass. Patient 2 was a 14-year-old boy who had severe cough, progressive mucocutaneous erosion, and dermatitis. Chest X-ray showed a mediastinal mass. Sections of skin biopsy showed findings consistent with pemphigus disease. In each case, the histological diagnosis of Castleman disease was made.
Original language | English |
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Pages (from-to) | 616-620 |
Number of pages | 5 |
Journal | Pediatric Blood and Cancer |
Volume | 47 |
Issue number | 5 |
DOIs | |
State | Published - 15 10 2006 |
Keywords
- Castleman disease
- Intrathoracic
- Paraneoplastic syndrome