Parathyroid carcinoma with postoperative prolonged hypocalcemia in a patient with chronic renal failure.

M. J. Liou*, J. D. Lin, M. J. Huang, J. Y. Huang, C. Hsueh, L. B. Jeng

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

6 Scopus citations

Abstract

Parathyroid carcinoma is a rare disease that usually presents with severe hypercalcemia and marked elevation of parathyroid hormone level. A 64-year-old male patient with repeated episodes of renal stones sustained chronic renal failure. Subsequently, he developed acute uremic symptoms and underwent a left upper parathyroidectomy. Parathyroid carcinoma was diagnosed after surgery. Asymptomatic hypocalcemia was the initial presentation. Protracted symptomatic hypocalcemia developed 8 months postoperatively, accompanied by an extremely high parathyroid hormone level. Delayed "bone hunger" syndrome concomitant with down-regulation of the parathyroid hormone receptors or production of parathyroid hormone with diminished bioactivity may have been the possible causes.

Original languageEnglish
Pages (from-to)337-341
Number of pages5
JournalJournal of the Formosan Medical Association
Volume95
Issue number4
StatePublished - 04 1996
Externally publishedYes

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