PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons

Medicine and Dentistry

• Reactive Oxygen Species 100%
• Phosphotransferase 100%
• Mutant 100%
• Mitochondrial Membrane Potential 100%
• Cells 23%
• Dopamine Agonist 23%
• Morphology 17%
• Mitochondrion 11%
• Neuroprotective Agent 11%
• Superoxide 5%
• Gene 5%
• Pathogenesis 5%
• Confocal Microscopy 5%
• Toxin 5%
• Protein Kinase 5%
• Programmed Cell Death 5%
• Oxidative Stress 5%
• Parkinson's Disease 5%
• Hydrogen Peroxide 5%
• Rotenone 5%
• Autosomal Recessive Inheritance 5%

Neuroscience

• Kinase 100%
• Substantia nigra 100%
• Dopaminergic Neuron 100%
• Mitochondrial Membrane Potential 100%
• Dopaminergic 23%
• Neuroprotective Agent 11%
• Mitochondrion 11%
• Parkinson's Disease 5%
• Gene 5%
• Oxidative Stress 5%
• Mitochondrial Function 5%
• Neuron 5%
• Rotenone 5%
• Protein Kinases 5%