Pathways for lactose/galactose catabolism by Streptococcus salivarius

Yi Ywan M. Chen; Matthew J. Betzenhauser; Jennifer A. Snyder; Robert A. Burne

doi:10.1016/S0378-1097(02)00472-X

Pathways for lactose/galactose catabolism by Streptococcus salivarius

Yi Ywan M. Chen, Matthew J. Betzenhauser, Jennifer A. Snyder, Robert A. Burne

Research output: Contribution to journal › Journal Article › peer-review

1 Scopus citations

Abstract

Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.

Original language	English
Pages (from-to)	72-76
Number of pages	5
Journal	FEMS Microbiology Letters
Volume	209
Issue number	1
DOIs	https://doi.org/10.1016/S0378-1097(02)00472-X
State	Published - 19 03 2002
Externally published	Yes

Keywords

Galactokinase
Leloir pathway
Streptococcus salivarius
β-Galactosidase

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10.1016/S0378-1097(02)00472-X

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title = "Pathways for lactose/galactose catabolism by Streptococcus salivarius",

abstract = "Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.",

keywords = "Galactokinase, Leloir pathway, Streptococcus salivarius, β-Galactosidase",

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AU - Betzenhauser, Matthew J.

AU - Snyder, Jennifer A.

AU - Burne, Robert A.

PY - 2002/3/19

Y1 - 2002/3/19

N2 - Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.

AB - Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.

KW - Galactokinase

KW - Leloir pathway

KW - Streptococcus salivarius

KW - β-Galactosidase

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Pathways for lactose/galactose catabolism by Streptococcus salivarius

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Keywords

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