Pathways for lactose/galactose catabolism by Streptococcus salivarius

Yi Ywan M. Chen; Matthew J. Betzenhauser; Jennifer A. Snyder; Robert A. Burne

doi:10.1016/s0378-1097(02)00472-x

Pathways for lactose/galactose catabolism by Streptococcus salivarius

Yi Ywan M. Chen
, Matthew J. Betzenhauser
, Jennifer A. Snyder
, Robert A. Burne^*

^*Corresponding author for this work

University of Florida

Research output: Contribution to journal › Journal Article › peer-review

Abstract

Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.

Original language	English
Pages (from-to)	75-79
Number of pages	5
Journal	FEMS Microbiology Letters
Volume	209
Issue number	1
DOIs	https://doi.org/10.1016/s0378-1097(02)00472-x
State	Published - 19 03 2002
Externally published	Yes

Keywords

Galactokinase
Leloir pathway
Streptococcus salivarius
β-Galactosidase

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10.1016/s0378-1097(02)00472-x

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title = "Pathways for lactose/galactose catabolism by Streptococcus salivarius",

abstract = "Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.",

keywords = "Galactokinase, Leloir pathway, Streptococcus salivarius, β-Galactosidase",

author = "Chen, \{Yi Ywan M.\} and Betzenhauser, \{Matthew J.\} and Snyder, \{Jennifer A.\} and Burne, \{Robert A.\}",

year = "2002",

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doi = "10.1016/s0378-1097(02)00472-x",

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AU - Chen, Yi Ywan M.

AU - Betzenhauser, Matthew J.

AU - Snyder, Jennifer A.

AU - Burne, Robert A.

PY - 2002/3/19

Y1 - 2002/3/19

N2 - Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.

AB - Galactokinase and β-galactosidase-deficient strains of Streptococcus salivarius were constructed to define the pathways for lactose and galactose catabolism. It was found that S. salivarius does not possess a lactose-specific phosphoenolpyruvate phosphotransferase system (PTS), that intracellular lactose was hydrolyzed by β-galactosidase, and that galactose is catabolized exclusively through the Leloir pathway. The lack of a high-affinity PTS for lactose may reflect the higher availability of the substrates to soft tissue organisms, such as S. salivarius, compared to dental plaque bacteria.

KW - Galactokinase

KW - Leloir pathway

KW - Streptococcus salivarius

KW - β-Galactosidase

UR - https://www.scopus.com/pages/publications/0037133748

U2 - 10.1016/s0378-1097(02)00472-x

DO - 10.1016/s0378-1097(02)00472-x

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AN - SCOPUS:0037133748

SN - 0378-1097

VL - 209

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EP - 79

JO - FEMS Microbiology Letters

JF - FEMS Microbiology Letters

IS - 1

ER -

Pathways for lactose/galactose catabolism by Streptococcus salivarius

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Keywords

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