Perforation of toxic megacolon in non-typhoid Salmonella enterocolitis spares young infants and is immune-mediated

Cherng-Hsun Chiu*, Lin-Hui Su, C. C. He, Tang-Her Jaing, Chih-cheng Luo, T. Y. Lin

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

9 Scopus citations

Abstract

Intestinal perforation, a life-threatening complication of toxic megacolon (TM) following non-typhoid Salmonella infection, is relatively uncommon in infants less than 1 year of age. The situation, also found in typhoid fever, appears to be cytokine-mediated. This finding may justify immunotherapy for older children with TM associated with non-typhoid Salmonella infection in order to prevent this complication.

Original languageEnglish
Pages (from-to)410-412
Number of pages3
JournalPediatric Surgery International
Volume18
Issue number5-6
DOIs
StatePublished - 09 2002

Keywords

  • Intestinal perforation
  • Salmonella
  • Toxic megacolon

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