Peripapillary fluorescein leakage in 11778 leber’s optic neuropathy

May Yung Yen*, Yau Huei Wei, Jorn Hon Liu

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

2 Scopus citations


A 17-year-old young man presented with a 2-month sequential visual loss in both eyes. Vision was 20/200 in the right eye and 20/400 in the left eye. Both discs were hyperemic with circumpapillary telangiectasia and nerve fiber swelling. Fluorescein angiography revealed a fuzzy hyperfluorescence due to leakage from dilated capillaries on both discs in the late transit. Molecular mitochondrial DNA study confirmed a homoplasmic 11778 Leber’s optic neuropathy.

Original languageEnglish
Pages (from-to)178-181
Number of pages4
JournalJournal of Neuro-Ophthalmology
Issue number3
StatePublished - 1996
Externally publishedYes


  • Leber’s optic neuropathy
  • Mitochondrial DNA mutation
  • Peripapillary fluorescein leakage


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