Abstract
Phenanthroindolizidine N-Oxide, ficuseptine-A (1), together with eighteen known compounds was isolated from the leaves of Ficus septica. The structures of these compounds were elucidated by spectroscopic analysis. Among them, phenanthroindolizidines, ficuseptine (1), (+)-tylophorine (4) and a mixture of (+)-tylocrebrine (5) and (+)-isotylocrebrine (6), exhibited strong cytotoxic activity against two human cancer cell lines, NUGC and HONE-1.
Original language | English |
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Pages (from-to) | 2401-2408 |
Number of pages | 8 |
Journal | Heterocycles |
Volume | 57 |
Issue number | 12 |
DOIs | |
State | Published - 01 12 2002 |
Externally published | Yes |