Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica

Pei Lin Wu; K. V. Rao; Chia Hao Su; Cheng Sheng Kuoh; Tian Shung Wu

doi:10.3987/COM-02-9615

Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica

Pei Lin Wu^*
, K. V. Rao
, Chia Hao Su
, Cheng Sheng Kuoh
, Tian Shung Wu

^*Corresponding author for this work

National Cheng Kung University

Research output: Contribution to journal › Journal Article › peer-review

67 Scopus citations

Abstract

Phenanthroindolizidine N-Oxide, ficuseptine-A (1), together with eighteen known compounds was isolated from the leaves of Ficus septica. The structures of these compounds were elucidated by spectroscopic analysis. Among them, phenanthroindolizidines, ficuseptine (1), (+)-tylophorine (4) and a mixture of (+)-tylocrebrine (5) and (+)-isotylocrebrine (6), exhibited strong cytotoxic activity against two human cancer cell lines, NUGC and HONE-1.

Original language	English
Pages (from-to)	2401-2408
Number of pages	8
Journal	Heterocycles
Volume	57
Issue number	12
DOIs	https://doi.org/10.3987/COM-02-9615
State	Published - 01 12 2002
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.3987/COM-02-9615

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title = "Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica",

abstract = "Phenanthroindolizidine N-Oxide, ficuseptine-A (1), together with eighteen known compounds was isolated from the leaves of Ficus septica. The structures of these compounds were elucidated by spectroscopic analysis. Among them, phenanthroindolizidines, ficuseptine (1), (+)-tylophorine (4) and a mixture of (+)-tylocrebrine (5) and (+)-isotylocrebrine (6), exhibited strong cytotoxic activity against two human cancer cell lines, NUGC and HONE-1.",

author = "Wu, \{Pei Lin\} and Rao, \{K. V.\} and Su, \{Chia Hao\} and Kuoh, \{Cheng Sheng\} and Wu, \{Tian Shung\}",

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doi = "10.3987/COM-02-9615",

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T1 - Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica

AU - Wu, Pei Lin

AU - Rao, K. V.

AU - Su, Chia Hao

AU - Kuoh, Cheng Sheng

AU - Wu, Tian Shung

PY - 2002/12/1

Y1 - 2002/12/1

N2 - Phenanthroindolizidine N-Oxide, ficuseptine-A (1), together with eighteen known compounds was isolated from the leaves of Ficus septica. The structures of these compounds were elucidated by spectroscopic analysis. Among them, phenanthroindolizidines, ficuseptine (1), (+)-tylophorine (4) and a mixture of (+)-tylocrebrine (5) and (+)-isotylocrebrine (6), exhibited strong cytotoxic activity against two human cancer cell lines, NUGC and HONE-1.

AB - Phenanthroindolizidine N-Oxide, ficuseptine-A (1), together with eighteen known compounds was isolated from the leaves of Ficus septica. The structures of these compounds were elucidated by spectroscopic analysis. Among them, phenanthroindolizidines, ficuseptine (1), (+)-tylophorine (4) and a mixture of (+)-tylocrebrine (5) and (+)-isotylocrebrine (6), exhibited strong cytotoxic activity against two human cancer cell lines, NUGC and HONE-1.

UR - https://www.scopus.com/pages/publications/0036899636

U2 - 10.3987/COM-02-9615

DO - 10.3987/COM-02-9615

M3 - 文章

AN - SCOPUS:0036899636

SN - 0385-5414

VL - 57

SP - 2401

EP - 2408

JO - Heterocycles

JF - Heterocycles

IS - 12

ER -

Phenanthroindolizidine alkaloids and their cytotoxicity from the leaves of Ficus septica

Abstract

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