Point-of-care based system development for urolithiasis recurrence prevention

W. Y. Chung; S. Heythem; A. Silverio; V. Tsai; C. Cheng; G. W. Wu; S. K. Chang; L. C. Yen; C. M. Yang; I. W. Lo; S. Y. Chang

doi:10.1149/08508.0175ecst

Point-of-care based system development for urolithiasis recurrence prevention

W. Y. Chung, S. Heythem, A. Silverio, V. Tsai, C. Cheng, G. W. Wu, S. K. Chang, L. C. Yen, C. M. Yang, I. W. Lo, S. Y. Chang

Graduate Institute of Electro-Optical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

This research presents a Point-Of-Care Test (POCT) system developed for urolithiasis recurrence prevention. The system can be used to assist a patient in assessing the condition of his urinary system through urine quality indicators pH, Ca²⁺, uric acid, conductivity, etc. Several major types of sensors were used to monitor key parameters in human's urine. Ion Sensitive Field Effect Transistor and Extended Gate Field Effect Transistor potentiometric-type sensors are used for pH and Ca²⁺ monitoring, the enzyme based two or three-electrode amperometric type sensor is used for urine's uric acid sensing, and the self-developed electrodes are used for conductivity measuring. The prototype with these sensors and CMOS readout circuits were integrated and tested in the laboratory and clinically. The test results show the acceptable and promising performance referred to corresponding meters for individual parameter sensing. Through the following. data analysis and risk evaluation by urologists, the developed POCT system has a potential value and contribution to kidney stone of urolithiasis recurrence prevention.

Original language	English
Title of host publication	ECS Transactions
Editors	Joao Antonio Martino, J. P. Raskin, S. Selberherr, H. Ishii, F. Gamiz, B. Y. Nguyen, A. Yoshino
Publisher	Electrochemical Society Inc.
Pages	175-186
Number of pages	12
Edition	8
ISBN (Electronic)	9781607688365
ISBN (Print)	9781607688365
DOIs	https://doi.org/10.1149/08508.0175ecst
State	Published - 2018
Event	Symposium on Advanced CMOS-Compatible Semiconductor Devices 18 - 233rd ECS Meeting - Seattle, United States Duration: 13 05 2018 → 17 05 2018

Publication series

Name	ECS Transactions
Number	8
Volume	85
ISSN (Print)	1938-6737
ISSN (Electronic)	1938-5862

Conference

Conference	Symposium on Advanced CMOS-Compatible Semiconductor Devices 18 - 233rd ECS Meeting
Country/Territory	United States
City	Seattle
Period	13/05/18 → 17/05/18

Bibliographical note

Publisher Copyright:
© The Electrochemical Society.

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10.1149/08508.0175ecst

Cite this

Chung, W. Y., Heythem, S., Silverio, A., Tsai, V., Cheng, C., Wu, G. W., Chang, S. K., Yen, L. C., Yang, C. M., Lo, I. W., & Chang, S. Y. (2018). Point-of-care based system development for urolithiasis recurrence prevention. In J. A. Martino, J. P. Raskin, S. Selberherr, H. Ishii, F. Gamiz, B. Y. Nguyen, & A. Yoshino (Eds.), ECS Transactions (8 ed., pp. 175-186). (ECS Transactions; Vol. 85, No. 8). Electrochemical Society Inc.. https://doi.org/10.1149/08508.0175ecst

@inproceedings{112a9ec25e2e4cf182e00a8a5c2a1fd9,

title = "Point-of-care based system development for urolithiasis recurrence prevention",

abstract = "This research presents a Point-Of-Care Test (POCT) system developed for urolithiasis recurrence prevention. The system can be used to assist a patient in assessing the condition of his urinary system through urine quality indicators pH, Ca2+, uric acid, conductivity, etc. Several major types of sensors were used to monitor key parameters in human's urine. Ion Sensitive Field Effect Transistor and Extended Gate Field Effect Transistor potentiometric-type sensors are used for pH and Ca2+ monitoring, the enzyme based two or three-electrode amperometric type sensor is used for urine's uric acid sensing, and the self-developed electrodes are used for conductivity measuring. The prototype with these sensors and CMOS readout circuits were integrated and tested in the laboratory and clinically. The test results show the acceptable and promising performance referred to corresponding meters for individual parameter sensing. Through the following. data analysis and risk evaluation by urologists, the developed POCT system has a potential value and contribution to kidney stone of urolithiasis recurrence prevention.",

author = "Chung, {W. Y.} and S. Heythem and A. Silverio and V. Tsai and C. Cheng and Wu, {G. W.} and Chang, {S. K.} and Yen, {L. C.} and Yang, {C. M.} and Lo, {I. W.} and Chang, {S. Y.}",

note = "Publisher Copyright: {\textcopyright} The Electrochemical Society.; Symposium on Advanced CMOS-Compatible Semiconductor Devices 18 - 233rd ECS Meeting ; Conference date: 13-05-2018 Through 17-05-2018",

year = "2018",

doi = "10.1149/08508.0175ecst",

language = "英语",

isbn = "9781607688365",

series = "ECS Transactions",

publisher = "Electrochemical Society Inc.",

number = "8",

pages = "175--186",

editor = "Martino, {Joao Antonio} and Raskin, {J. P.} and S. Selberherr and H. Ishii and F. Gamiz and Nguyen, {B. Y.} and A. Yoshino",

booktitle = "ECS Transactions",

edition = "8",

}

Chung, WY, Heythem, S, Silverio, A, Tsai, V, Cheng, C, Wu, GW, Chang, SK, Yen, LC, Yang, CM, Lo, IW & Chang, SY 2018, Point-of-care based system development for urolithiasis recurrence prevention. in JA Martino, JP Raskin, S Selberherr, H Ishii, F Gamiz, BY Nguyen & A Yoshino (eds), ECS Transactions. 8 edn, ECS Transactions, no. 8, vol. 85, Electrochemical Society Inc., pp. 175-186, Symposium on Advanced CMOS-Compatible Semiconductor Devices 18 - 233rd ECS Meeting, Seattle, United States, 13/05/18. https://doi.org/10.1149/08508.0175ecst

Point-of-care based system development for urolithiasis recurrence prevention. / Chung, W. Y.; Heythem, S.; Silverio, A. et al.
ECS Transactions. ed. / Joao Antonio Martino; J. P. Raskin; S. Selberherr; H. Ishii; F. Gamiz; B. Y. Nguyen; A. Yoshino. 8. ed. Electrochemical Society Inc., 2018. p. 175-186 (ECS Transactions; Vol. 85, No. 8).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Point-of-care based system development for urolithiasis recurrence prevention

AU - Chung, W. Y.

AU - Heythem, S.

AU - Silverio, A.

AU - Tsai, V.

AU - Cheng, C.

AU - Wu, G. W.

AU - Chang, S. K.

AU - Yen, L. C.

AU - Yang, C. M.

AU - Lo, I. W.

AU - Chang, S. Y.

N1 - Publisher Copyright: © The Electrochemical Society.

PY - 2018

Y1 - 2018

N2 - This research presents a Point-Of-Care Test (POCT) system developed for urolithiasis recurrence prevention. The system can be used to assist a patient in assessing the condition of his urinary system through urine quality indicators pH, Ca2+, uric acid, conductivity, etc. Several major types of sensors were used to monitor key parameters in human's urine. Ion Sensitive Field Effect Transistor and Extended Gate Field Effect Transistor potentiometric-type sensors are used for pH and Ca2+ monitoring, the enzyme based two or three-electrode amperometric type sensor is used for urine's uric acid sensing, and the self-developed electrodes are used for conductivity measuring. The prototype with these sensors and CMOS readout circuits were integrated and tested in the laboratory and clinically. The test results show the acceptable and promising performance referred to corresponding meters for individual parameter sensing. Through the following. data analysis and risk evaluation by urologists, the developed POCT system has a potential value and contribution to kidney stone of urolithiasis recurrence prevention.

AB - This research presents a Point-Of-Care Test (POCT) system developed for urolithiasis recurrence prevention. The system can be used to assist a patient in assessing the condition of his urinary system through urine quality indicators pH, Ca2+, uric acid, conductivity, etc. Several major types of sensors were used to monitor key parameters in human's urine. Ion Sensitive Field Effect Transistor and Extended Gate Field Effect Transistor potentiometric-type sensors are used for pH and Ca2+ monitoring, the enzyme based two or three-electrode amperometric type sensor is used for urine's uric acid sensing, and the self-developed electrodes are used for conductivity measuring. The prototype with these sensors and CMOS readout circuits were integrated and tested in the laboratory and clinically. The test results show the acceptable and promising performance referred to corresponding meters for individual parameter sensing. Through the following. data analysis and risk evaluation by urologists, the developed POCT system has a potential value and contribution to kidney stone of urolithiasis recurrence prevention.

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DO - 10.1149/08508.0175ecst

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SN - 9781607688365

T3 - ECS Transactions

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EP - 186

BT - ECS Transactions

A2 - Martino, Joao Antonio

A2 - Raskin, J. P.

A2 - Selberherr, S.

A2 - Ishii, H.

A2 - Gamiz, F.

A2 - Nguyen, B. Y.

A2 - Yoshino, A.

PB - Electrochemical Society Inc.

T2 - Symposium on Advanced CMOS-Compatible Semiconductor Devices 18 - 233rd ECS Meeting

Y2 - 13 May 2018 through 17 May 2018

ER -

Point-of-care based system development for urolithiasis recurrence prevention

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