@inproceedings{69ffb36e579841d994e355b5cb2e88f3,
title = "Polyacrylic acid-derivatized superparamagnetic iron oxide nanoparticles for delivery of tissue plasminogen activator",
abstract = "Polyacrylic acid (PAA)-derivatized Fe3O4 magnetic nanoparticle (MNP) intended as a drug carrier were synthesized by two different approaches and studied for chemicophysical properties. PAA-MNP prepared by physical adsorption of PAA on pre-formed MNP showed better properties for covalent binding with a thrombolytic drug, recombinant tissue plasminogen activator (rtPA). The PAA-MNP-rtPA conjugate showed full retention of thrombolytic activity and is useful as a magnetically targeted drug carrier to improve clinical thrombolytic therapy.",
author = "Chen, {Jyh Ping} and Yang, {Pei Chin} and Hwang, {Hwei Fang}",
year = "2010",
doi = "10.1109/INEC.2010.5424830",
language = "英语",
isbn = "9781424435449",
series = "INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings",
pages = "1391--1392",
booktitle = "INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings",
note = "2010 3rd International Nanoelectronics Conference, INEC 2010 ; Conference date: 03-01-2010 Through 08-01-2010",
}