Abstract
Background/Aim: Restriction of mouth opening (RMO) is a common manifestation of head and neck cancer (HNC) and a poor prognostic factor following concurrent chemoradiotherapy (CCRT) of patients. This study aimed to explore whether the Mallampati score, a visual assessment of the distance from the tongue base to the roof of the mouth, can be used as a surrogate for RMO in predicting treatment outcomes in patients with HNC undergoing CCRT. Patients and Methods: A total of 461 consecutive patients who received definitive CCRT for the treatment of locally advanced HNC between August 2016 and December 2017 at Chang Gung Memorial Hospital in Taiwan (Linkou, Keelung, and Kaohsiung branches) were enrolled in this prospective study. Patients were allocated by the pre-treatment Mallampati score of 1 or 2 (n=24) vs. 3 or 4 (n=207) to compare treatment compliance and treatment-related complications.
| Original language | English |
|---|---|
| Pages (from-to) | 5609-5618 |
| Number of pages | 10 |
| Journal | Anticancer Research |
| Volume | 42 |
| Issue number | 11 |
| DOIs | |
| State | Published - 11 2022 |
Bibliographical note
Publisher Copyright:© 2022 International Institute of Anticancer Research. All rights reserved.
Keywords
- Mallampati score
- chemoradiotherapy
- head and neck cancer
- outcome
- restricted mouth opening
- trismus