Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic

Chia Ming Chu; Chau Ting Yeh; Cheng Tang Chiu; I. Shyan Sheen; Yun Fan Liaw

doi:10.1128/jcm.34.7.1815-1818.1996

Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic

Chia Ming Chu^*, Chau Ting Yeh, Cheng Tang Chiu, I. Shyan Sheen, Yun Fan Liaw

^*Corresponding author for this work

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

38 Scopus citations

Abstract

By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. The precore TAG mutant prevails in acute and chronic hepatitis B of various severity in this area where hepatitis B is endemic.

Original language	English
Pages (from-to)	1815-1818
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	34
Issue number	7
DOIs	https://doi.org/10.1128/jcm.34.7.1815-1818.1996
State	Published - 07 1996
Externally published	Yes

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10.1128/jcm.34.7.1815-1818.1996

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title = "Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic",

abstract = "By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. The precore TAG mutant prevails in acute and chronic hepatitis B of various severity in this area where hepatitis B is endemic.",

author = "Chu, {Chia Ming} and Yeh, {Chau Ting} and Chiu, {Cheng Tang} and Sheen, {I. Shyan} and Liaw, {Yun Fan}",

year = "1996",

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doi = "10.1128/jcm.34.7.1815-1818.1996",

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AU - Chu, Chia Ming

AU - Yeh, Chau Ting

AU - Chiu, Cheng Tang

AU - Sheen, I. Shyan

AU - Liaw, Yun Fan

PY - 1996/7

Y1 - 1996/7

N2 - By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. The precore TAG mutant prevails in acute and chronic hepatitis B of various severity in this area where hepatitis B is endemic.

AB - By using an amplification-created restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute fulminant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatitis B patients, 35 (81%) of 43 hepatitis B virus surface antigen carriers with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surface antigen carriers with chronic hepatitis. The precore TAG mutant prevails in acute and chronic hepatitis B of various severity in this area where hepatitis B is endemic.

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U2 - 10.1128/jcm.34.7.1815-1818.1996

DO - 10.1128/jcm.34.7.1815-1818.1996

M3 - 文章

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AN - SCOPUS:0029891071

SN - 0095-1137

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JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 7

ER -

Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic

Abstract

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