Predicting clinically significant changes in motor and functional outcomes after robot-assisted stroke rehabilitation

Yu Wei Hsieh, Keh Chung Lin, Ching Yi Wu*, Hen Yu Lien, Jean Lon Chen, Chih Chi Chen, Wei Han Chang

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

34 Scopus citations

Abstract

Objective To investigate the predictors of minimal clinically important changes on outcome measures after robot-assisted therapy (RT). Design Observational cohort study. Setting Outpatient rehabilitation clinics. Participants A cohort of outpatients with stroke (N=55). Interventions Patients with stroke received RT for 90 to 105min/d, 5d/wk, for 4 weeks. Main Outcome Measures Outcome measures, including the Fugl-Meyer Assessment (FMA) and Motor Activity Log (MAL), were measured before and after the intervention. Potential predictors include age, sex, side of lesion, time since stroke onset, finger extension, Box and Block Test (BBT) score, and FMA distal score. Results Statistical analysis showed that the BBT score (odds ratio[OR]=1.06; P=.04) was a significant predictor of clinically important changes in the FMA. Being a woman (OR=3.9; P=.05) and BBT score (OR=1.07; P=.02) were the 2 significant predictors of clinically significant changes in the MAL amount of use subscale. The BBT score was the significant predictor of an increased probability of achieving clinically important changes in the MAL quality of movement subscale (OR=1.07; P=.02). The R2 values for the 3 logistic regression models were low (.114-.272). Conclusions The results revealed that patients with stroke who had greater manual dexterity measured by the BBT appear to have a higher probability of achieving clinically significant motor and functional outcomes after RT. Further studies are needed to evaluate other potential predictors to improve the models and validate the findings.

Original languageEnglish
Pages (from-to)316-321
Number of pages6
JournalArchives of Physical Medicine and Rehabilitation
Volume95
Issue number2
DOIs
StatePublished - 02 2014

Keywords

  • Prognosis
  • Rehabilitation
  • Stroke

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