TY - JOUR
T1 - Predictive factors for lymph node metastasis in early gastric cancer
AU - Sung, Chang Mu
AU - Hsu, Chen Ming
AU - Hsu, Jun Te
AU - Yeh, Ta Sen
AU - Lin, Chun Jung
AU - Chen, Tse Ching
AU - Su, Ming Yao
AU - Chiu, Cheng Tang
PY - 2010/11/7
Y1 - 2010/11/7
N2 - AIM: To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS: Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM. RESULTS: Of the 2936 patients who underwent gastrectomy and lymph node dissection, 556 were diagnosed with EGC and included in this study. Among these, 4.1% of patients had mucosal tumors (T1a) with LNM while 24.3% of patients had submucosal tumors with LNM. Univariate analysis found that female gender, tumors ≥ 2 cm, tumor invasion to the submucosa, vascular and lymphatic involvement were significantly associated with a higher rate of LNM. On multivariate analysis, tumor size, lymphatic involvement, and tumor with submucosal invasion were associated with LNM. CONCLUSION: Tumor with submucosal invasion, size ≥ 2 cm, and presence of lymphatic involvement are predictive factors for LNM in EGC.
AB - AIM: To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS: Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM. RESULTS: Of the 2936 patients who underwent gastrectomy and lymph node dissection, 556 were diagnosed with EGC and included in this study. Among these, 4.1% of patients had mucosal tumors (T1a) with LNM while 24.3% of patients had submucosal tumors with LNM. Univariate analysis found that female gender, tumors ≥ 2 cm, tumor invasion to the submucosa, vascular and lymphatic involvement were significantly associated with a higher rate of LNM. On multivariate analysis, tumor size, lymphatic involvement, and tumor with submucosal invasion were associated with LNM. CONCLUSION: Tumor with submucosal invasion, size ≥ 2 cm, and presence of lymphatic involvement are predictive factors for LNM in EGC.
KW - Depth of tumor invasion
KW - Early gastric cancer
KW - Endoscopic submucosa dissection
KW - Endoscopic treatment
KW - Lymph node metastasis
UR - http://www.scopus.com/inward/record.url?scp=78649406815&partnerID=8YFLogxK
U2 - 10.3748/wjg.v16.i41.5252
DO - 10.3748/wjg.v16.i41.5252
M3 - 文章
C2 - 21049560
AN - SCOPUS:78649406815
SN - 1007-9327
VL - 16
SP - 5252
EP - 5256
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
IS - 41
ER -
