TY - JOUR
T1 - Pregnancy with Essential Thrombocythemia
T2 - A Case Report
AU - Chou, Yin Jou
AU - Ou, Yu Che
AU - Chang, Shiuh Young
AU - Hsu, Te Yao
PY - 2004/12
Y1 - 2004/12
N2 - Objective: We describe a woman with essential thrombocythemia (ET) who experienced a successful pregnancy with no specific treatment. Case Report: A 30-year-old primiparous female was incidentally found to have ET with no specific symptoms at a gestational age (GA) of 8 weeks. Initially, her platelet count was 1,100 × 109/L, which declined to a median of 678 × 109/L (range, 663-753 × 109/L) during the second and third trimesters, without treatment. A healthy male baby weighing 3,330 g was born by cesarean delivery due to breech presentation at a GA of 38 weeks. The pre-delivery platelet count was 605 × 109/L. No bleeding or major thromboembolic complications were encountered in the peripartum period. The maternal platelet count returned to 1,230 × 109/L and 1,320 × 109/L, respectively, at 2 months and 3 years after delivery. The child had normal physical and mental development at 2 years and 9 months old. Conclusion: Management of ET during pregnancy is still controversial. Platelet count, either at diagnosis or at conception, fails to predict the pregnancy outcome. The treatment plan should be based on clinical judgment that weighs the risk of thrombohemorrhagic complications against related morbidity and side effects.
AB - Objective: We describe a woman with essential thrombocythemia (ET) who experienced a successful pregnancy with no specific treatment. Case Report: A 30-year-old primiparous female was incidentally found to have ET with no specific symptoms at a gestational age (GA) of 8 weeks. Initially, her platelet count was 1,100 × 109/L, which declined to a median of 678 × 109/L (range, 663-753 × 109/L) during the second and third trimesters, without treatment. A healthy male baby weighing 3,330 g was born by cesarean delivery due to breech presentation at a GA of 38 weeks. The pre-delivery platelet count was 605 × 109/L. No bleeding or major thromboembolic complications were encountered in the peripartum period. The maternal platelet count returned to 1,230 × 109/L and 1,320 × 109/L, respectively, at 2 months and 3 years after delivery. The child had normal physical and mental development at 2 years and 9 months old. Conclusion: Management of ET during pregnancy is still controversial. Platelet count, either at diagnosis or at conception, fails to predict the pregnancy outcome. The treatment plan should be based on clinical judgment that weighs the risk of thrombohemorrhagic complications against related morbidity and side effects.
KW - essential thrombocythemia
KW - pregnancy
UR - https://www.scopus.com/pages/publications/67651097742
U2 - 10.1016/S1028-4559(09)60096-6
DO - 10.1016/S1028-4559(09)60096-6
M3 - 文章
AN - SCOPUS:67651097742
SN - 1028-4559
VL - 43
SP - 237
EP - 239
JO - Taiwanese Journal of Obstetrics and Gynecology
JF - Taiwanese Journal of Obstetrics and Gynecology
IS - 4
ER -