TY - JOUR
T1 - Preparation of β-cyclodextrin entrapped graphite composite for sensitive detection of dopamine
AU - Palanisamy, Selvakumar
AU - Sakthinathan, S.
AU - Chen, Shen Ming
AU - Thirumalraj, Balamurugan
AU - Wu, Tsung Han
AU - Lou, Bih Show
AU - Liu, Xiaoheng
PY - 2016/1/1
Y1 - 2016/1/1
N2 - A simple dopamine (DA) electrochemical sensor was developed based on a screen-printed carbon electrode (SPCE) modified with β-cyclodextrin entrapped graphite (GR/β-CD) composite for the first time. The polar hydroxyl groups on the β-CD rims interact with polar groups of edges of GR sheets resulting into the high dispersion ability of GR in β-CD solution. The GR/β-CD modified electrode exhibited a higher electrochemical response to DA with a lower oxidation potential (0.224 V) than that of bare/β-CD (0.38 V) and GR (0.525 V) modified SPCEs, revealing an excellent electro-oxidation behavior of GR/β-CD composite toward DA. Under optimum conditions, the fabricated sensor detects the DA in the linear concentration range from 0.1 to 58.5 μM with a limit of detection of 0.011 μM and the sensitivity of 1.27 ± 0.02 μA μM-1 cm-2. The fabricated sensor also exhibits the excellent repeatability, practicality, reproducibility, storage stability along with acceptable selectivity. 7copy; 2015 Elsevier Ltd. All rights reserved.
AB - A simple dopamine (DA) electrochemical sensor was developed based on a screen-printed carbon electrode (SPCE) modified with β-cyclodextrin entrapped graphite (GR/β-CD) composite for the first time. The polar hydroxyl groups on the β-CD rims interact with polar groups of edges of GR sheets resulting into the high dispersion ability of GR in β-CD solution. The GR/β-CD modified electrode exhibited a higher electrochemical response to DA with a lower oxidation potential (0.224 V) than that of bare/β-CD (0.38 V) and GR (0.525 V) modified SPCEs, revealing an excellent electro-oxidation behavior of GR/β-CD composite toward DA. Under optimum conditions, the fabricated sensor detects the DA in the linear concentration range from 0.1 to 58.5 μM with a limit of detection of 0.011 μM and the sensitivity of 1.27 ± 0.02 μA μM-1 cm-2. The fabricated sensor also exhibits the excellent repeatability, practicality, reproducibility, storage stability along with acceptable selectivity. 7copy; 2015 Elsevier Ltd. All rights reserved.
KW - Differential pulse voltammetry
KW - Dopamine
KW - Graphite
KW - Screen-printed carbon electrode
KW - β-Cyclodextrin
UR - http://www.scopus.com/inward/record.url?scp=84941671070&partnerID=8YFLogxK
U2 - 10.1016/j.carbpol.2015.09.008
DO - 10.1016/j.carbpol.2015.09.008
M3 - 文章
C2 - 26453877
AN - SCOPUS:84941671070
SN - 0144-8617
VL - 135
SP - 267
EP - 273
JO - Carbohydrate Polymers
JF - Carbohydrate Polymers
ER -