Preparation of composite electrospun nanofibers of polycaprolactone and nanohydroxyapatite for osteogenic differentiation of stem cells

  • Jyh Ping Chen*
  • , Guo Chun Lai
  • , Yin Shin Chang
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Nanocomposites of poly(ε-caprolactone) (PCL) and nanohydroxyapatite (nHAP) were prepared by electrospinning to produce 300 nm nanofibers containing 0 , 25, and 50 wt% of nHAP. The composite nanofibers were characterized for structure, morphology, and mechanical properties. Mesenchymal stem cells grown on the nanofibers show different degree of osteogenic differentiation dependent on nHAP content with the highest nHAP content giving the best mineralization.

Original languageEnglish
Title of host publicationINEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings
Pages1395-1396
Number of pages2
DOIs
StatePublished - 2010
Event2010 3rd International Nanoelectronics Conference, INEC 2010 - Hongkong, China
Duration: 03 01 201008 01 2010

Publication series

NameINEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings

Conference

Conference2010 3rd International Nanoelectronics Conference, INEC 2010
Country/TerritoryChina
CityHongkong
Period03/01/1008/01/10

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