Prevalence of antibodies to hepatitis C virus in the hemodialysis unit

H. H. Lin; C. C. Huang; I. S. Sheen; D. Y. Lin; Y. F. Liaw

doi:10.1159/000168302

Prevalence of antibodies to hepatitis C virus in the hemodialysis unit

H. H. Lin, C. C. Huang, I. S. Sheen, D. Y. Lin, Y. F. Liaw

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

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Abstract

An enzyme immunoassay was used to detect antibodies to hepatitis C virus (anti-HCV) in 261 patients and 69 staff members of a hemodialysis unit.The prevalence of anti-HCV was 46.7% in patients and 2.9% in staff members (p < 0.001). The prevalence of anti-HCV increased significantly with increasing duration of hemodialysis (p < 0.001), but was not related to age, sex, history of blood transfusion, status of hepatitis B or hepatitis A virus infection, or serum ALT. Patients with hepatitis episode increased with increasing duration of hemodialysis and showed a significantly higher prevalence of anti-HCV than those without (63.1 vs. 34.7%, p < 0.001). The prevalence of anti-HCV in patients with hepatitis also increased with increasing duration of hemodialysis (p = 0.05). Thus, HCV appears to be the major cause of hepatitis in hemodialysis patients. Besides strict infection control measures, further studies are needed to determine the mode of HCV infection and its prevention in the hemodialysis unit.

Original language	English
Pages (from-to)	192-194
Number of pages	3
Journal	American Journal of Nephrology
Volume	11
Issue number	3
DOIs	https://doi.org/10.1159/000168302
State	Published - 1991
Externally published	Yes

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title = "Prevalence of antibodies to hepatitis C virus in the hemodialysis unit",

abstract = "An enzyme immunoassay was used to detect antibodies to hepatitis C virus (anti-HCV) in 261 patients and 69 staff members of a hemodialysis unit.The prevalence of anti-HCV was 46.7% in patients and 2.9% in staff members (p < 0.001). The prevalence of anti-HCV increased significantly with increasing duration of hemodialysis (p < 0.001), but was not related to age, sex, history of blood transfusion, status of hepatitis B or hepatitis A virus infection, or serum ALT. Patients with hepatitis episode increased with increasing duration of hemodialysis and showed a significantly higher prevalence of anti-HCV than those without (63.1 vs. 34.7%, p < 0.001). The prevalence of anti-HCV in patients with hepatitis also increased with increasing duration of hemodialysis (p = 0.05). Thus, HCV appears to be the major cause of hepatitis in hemodialysis patients. Besides strict infection control measures, further studies are needed to determine the mode of HCV infection and its prevention in the hemodialysis unit.",

author = "Lin, {H. H.} and Huang, {C. C.} and Sheen, {I. S.} and Lin, {D. Y.} and Liaw, {Y. F.}",

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T1 - Prevalence of antibodies to hepatitis C virus in the hemodialysis unit

AU - Lin, H. H.

AU - Huang, C. C.

AU - Sheen, I. S.

AU - Lin, D. Y.

AU - Liaw, Y. F.

PY - 1991

Y1 - 1991

N2 - An enzyme immunoassay was used to detect antibodies to hepatitis C virus (anti-HCV) in 261 patients and 69 staff members of a hemodialysis unit.The prevalence of anti-HCV was 46.7% in patients and 2.9% in staff members (p < 0.001). The prevalence of anti-HCV increased significantly with increasing duration of hemodialysis (p < 0.001), but was not related to age, sex, history of blood transfusion, status of hepatitis B or hepatitis A virus infection, or serum ALT. Patients with hepatitis episode increased with increasing duration of hemodialysis and showed a significantly higher prevalence of anti-HCV than those without (63.1 vs. 34.7%, p < 0.001). The prevalence of anti-HCV in patients with hepatitis also increased with increasing duration of hemodialysis (p = 0.05). Thus, HCV appears to be the major cause of hepatitis in hemodialysis patients. Besides strict infection control measures, further studies are needed to determine the mode of HCV infection and its prevention in the hemodialysis unit.

AB - An enzyme immunoassay was used to detect antibodies to hepatitis C virus (anti-HCV) in 261 patients and 69 staff members of a hemodialysis unit.The prevalence of anti-HCV was 46.7% in patients and 2.9% in staff members (p < 0.001). The prevalence of anti-HCV increased significantly with increasing duration of hemodialysis (p < 0.001), but was not related to age, sex, history of blood transfusion, status of hepatitis B or hepatitis A virus infection, or serum ALT. Patients with hepatitis episode increased with increasing duration of hemodialysis and showed a significantly higher prevalence of anti-HCV than those without (63.1 vs. 34.7%, p < 0.001). The prevalence of anti-HCV in patients with hepatitis also increased with increasing duration of hemodialysis (p = 0.05). Thus, HCV appears to be the major cause of hepatitis in hemodialysis patients. Besides strict infection control measures, further studies are needed to determine the mode of HCV infection and its prevention in the hemodialysis unit.

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Prevalence of antibodies to hepatitis C virus in the hemodialysis unit

Abstract

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