Prevalence of human papillomavirus genotypes in northern taiwanese women

Kuo Chien Tsao, Chung Guei Huang, Yung Bin Kuo, Ting Chang Chang, Chien Feng Sun, C. Allen Chang, Su Li Yang, Err Cheng Chan*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

17 Scopus citations


The prevalence of Human Papillomavirus (HPV) in the general population of northern Taiwan is described. A total of 343 consecutive cervical swabs from women visiting the medical center for routine gynecologic care were included. Cervical cell cytology was examined by the Papanicolaou (Pap) test, and a PCR-based hybridization gene chip analysis was used to identify HPV genotypes. The HPV prevalence in the overall population was 32.4%. When divided into two groups according to cytology, 20.9% of women with normal cytology were HPV positive while 75.3% of women with abnormal cytology were HPV positive. Among positive samples, 68.5% were single type infections while 31.5% harbored multiple HPV types. A total of 32 types of HPV were identified; the leading five were HPV16 (5.8%), HPV58 (5.3%), HPV53 (4.1%), HPV52 (3.8%), and HPV18 (2.3%). Our results constitute baseline data and may provide important implications for future prophylactic programs. The relatively high prevalence of HPV 58, 53, and 52 among northern Taiwanese women has important implications for vaccine development.

Original languageEnglish
Pages (from-to)1739-1745
Number of pages7
JournalJournal of Medical Virology
Issue number10
StatePublished - 10 2010


  • Distribution
  • Genotype
  • Human papillomavirus


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