Proliferation and characterisation of meniscal chondrocytes on collagen beads

S. W. Tsai*, J. A. Werkmeister, T. A. Tebb, J. F. White, V. Glattauer, W. B. Tsai, J. A.M. Ramshaw

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


The growth and type of matrix generation of meniscal cells cultured on a novel porous 3D collagen gel bead system was investigated. The size and shape of the beads was found to be dependent on the concentration of collagen and alginate, the rate of flow of the mixture into CaCl2, and the rate of stirring. It was observed that mixed populations of chondrocytic cells can be isolated from sheep menisci and proliferated in a porous fibrous collagen type I bead in spinner cultures. It was found that larger numbers of cells can be readily expanded in culture and new matrix deposition demonstrated similar to native tissue.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 05 200421 05 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


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