Abstract
Induction of neural stem/progenitor cells (NSPCs) and establishment of neural network are important issues on neural engineering. In this work, a platform was designed to control and evaluate the differentiation of NSPCs, neurite direction, and to promote the neurite outgrowth. Polyelectrolyte multilayer (PEM) films provide surface properties by and have been used to regulate NSPCs differentiation in our previous study. Herein, a culture platform composed of SU-8 microchannel and PEM films was designed to achieve the goal of promoting NSPCs differentiation and to evaluate the effect of PEM films on the guidance of neural network formation. In this culture platform, NSPCs were induced into functional neurons, and neural network formation was accomplished on ITO glass-PEM films successfully.
Original language | English |
---|---|
Title of host publication | 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 4447-4450 |
Number of pages | 4 |
ISBN (Electronic) | 9781457702204 |
DOIs | |
State | Published - 13 10 2016 |
Event | 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States Duration: 16 08 2016 → 20 08 2016 |
Publication series
Name | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
---|---|
Volume | 2016-October |
ISSN (Print) | 1557-170X |
Conference
Conference | 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 |
---|---|
Country/Territory | United States |
City | Orlando |
Period | 16/08/16 → 20/08/16 |
Bibliographical note
Publisher Copyright:© 2016 IEEE.