Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies

J. A. Montaraz; A. J. Winter; D. M. Hunter; B. A. Sowa; A. M. Wu; L. G. Adams

doi:10.1128/iai.51.3.961-963.1986

Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies

J. A. Montaraz
, A. J. Winter
, D. M. Hunter
, B. A. Sowa
, A. M. Wu
, L. G. Adams

Cornell University College of Veterinary Medicine
Universidad Nacional Autónoma de México
Texas A&M University

Research output: Contribution to journal › Journal Article › peer-review

79 Scopus citations

Abstract

Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.

Original language	English
Pages (from-to)	961-963
Number of pages	3
Journal	Infection and Immunity
Volume	51
Issue number	3
DOIs	https://doi.org/10.1128/iai.51.3.961-963.1986
State	Published - 1986
Externally published	Yes

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10.1128/iai.51.3.961-963.1986

Cite this

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title = "Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies",

abstract = "Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.",

author = "Montaraz, \{J. A.\} and Winter, \{A. J.\} and Hunter, \{D. M.\} and Sowa, \{B. A.\} and Wu, \{A. M.\} and Adams, \{L. G.\}",

year = "1986",

doi = "10.1128/iai.51.3.961-963.1986",

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AU - Montaraz, J. A.

AU - Winter, A. J.

AU - Hunter, D. M.

AU - Sowa, B. A.

AU - Wu, A. M.

AU - Adams, L. G.

PY - 1986

Y1 - 1986

N2 - Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.

AB - Mice injected with either of two monoclonal antibodies specific for the O polysaccharide of Brucella abortus prior to challenge infection had viable counts in spleens and livers significantly below those in control groups 1 and 4 weeks later. Two monoclonal antibodies specific for the porin of B. abortus failed to confer protection.

UR - https://www.scopus.com/pages/publications/0022576612

U2 - 10.1128/iai.51.3.961-963.1986

DO - 10.1128/iai.51.3.961-963.1986

M3 - 文章

C2 - 3005173

AN - SCOPUS:0022576612

SN - 0019-9567

VL - 51

SP - 961

EP - 963

JO - Infection and Immunity

JF - Infection and Immunity

IS - 3

ER -

Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies

Abstract

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