Abstract
A subgroup of patients with Kawasaki disease (KD) did not respond to intravenous immune globulin (IVIG) therapy. Corticosteroid therapy remains a controversial alternative in such cases. We report two young children with KD who failed to respond to three courses of IVIG therapy and subsequently received pulse methylprednisolone as an alternative. One had a satisfactory outcome but the other developed giant coronary aneurysms and had a myocardial infarction 2 months after onset of the illness. A review of relevant literature showed that the timing of initiation of pulse methylprednisolone therapy is importar. It is suggested that pulse methylprednisolone therapy should be considered if there is no response to two standard doses of IVIG treatment.
Original language | English |
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Pages (from-to) | 89-93 |
Number of pages | 5 |
Journal | Annals of Tropical Paediatrics |
Volume | 24 |
Issue number | 1 |
DOIs | |
State | Published - 03 2004 |
Externally published | Yes |