Pushing CT and MR imaging to the molecular level for studying the "omics": Current challenges and advancements

Hsuan Ming Huang, Yi Yu Shih*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

During the past decade, medical imaging has made the transition from anatomical imaging to functional and even molecular imaging. Such transition provides a great opportunity to begin the integration of imaging data and various levels of biological data. In particular, the integration of imaging data and multiomics data such as genomics, metabolomics, proteomics, and pharmacogenomics may open new avenues for predictive, preventive, and personalized medicine. However, to promote imaging-omics integration, the practical challenge of imaging techniques should be addressed. In this paper, we describe key challenges in two imaging techniques: computed tomography (CT) and magnetic resonance imaging (MRI) and then review existing technological advancements. Despite the fact that CT and MRI have different principles of image formation, both imaging techniques can provide high-resolution anatomical images while playing a more and more important role in providing molecular information. Such imaging techniques that enable single modality to image both the detailed anatomy and function of tissues and organs of the body will be beneficial in the imaging-omics field.

Original languageEnglish
Article number365812
JournalBioMed Research International
Volume2014
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Dive into the research topics of 'Pushing CT and MR imaging to the molecular level for studying the "omics": Current challenges and advancements'. Together they form a unique fingerprint.

Cite this