Radiation-induced skull base leiomyosarcoma presenting with intracerebral haemorrhage.

C. H. Toh*, H. F. Wong, S. M. Jung, A. M. Wong

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

9 Scopus citations


Radiation-induced neoplasm including meningioma, glioma and sarcoma, is an uncommon but known consequence after therapeutic irradiation of pituitary tumour. Radiation-induced leiomyosarcoma due to previous sellar irradiation has only been reported once in the literature. We herein present the second case of radiation-induced leiomyosarcoma that happened 17 years after radiation therapy for pituitary adenoma. The case is unique in its initial presentation, i.e. acute intracerebral haemorrhage. To the best of our knowledge, such an acute and severe presentation has never been reported in radiation-induced neoplasm following radiotherapy for pituitary adenoma.

Original languageEnglish
Pages (from-to)e212-215
JournalBritish Journal of Radiology
Issue number957
StatePublished - 2007


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