RAG-2 Unleashed: Lymphocytes Beware

Sebastian D. Fugmann*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

The programmed degradation of the RAG-2 enzyme upon entry to S phase restricts V(D)J recombination to the G0-G1 phase of the cell cycle. In this issue of Immunity, Zhang et al. (2011) show that this is critical to prevent lymphoma formation.

Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalImmunity
Volume34
Issue number2
DOIs
StatePublished - 25 02 2011
Externally publishedYes

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