Recent advancements in aptamer-based surface plasmon resonance biosensing strategies

Chia Chen Chang

doi:10.3390/bios11070233

Recent advancements in aptamer-based surface plasmon resonance biosensing strategies

Chia Chen Chang^*

^*Corresponding author for this work

Department of Medical Biotechnology and Laboratory Science

Chang Gung Memorial Hospital

Research output: Contribution to journal › Review article › peer-review

47 Scopus citations

Abstract

Surface plasmon resonance (SPR) can track molecular interactions in real time, and is a powerful as well as widely used biological and chemical sensing technique. Among the different SPR-based sensing applications, aptamer-based SPR biosensors have attracted significant attention because of their simplicity, feasibility, and low cost for target detection. Continuous developments in SPR aptasensing research have led to the emergence of abundant technical and design concepts. To understand the recent advances in SPR for biosensing, this paper reviews SPR-based research from the last seven years based on different sensing-type strategies and sub-directions. The characteristics of various SPR-based applications are introduced. We hope that this review will guide the development of SPR aptamer sensors for healthcare.

Original language	English
Article number	233
Journal	Biosensors
Volume	11
Issue number	7
DOIs	https://doi.org/10.3390/bios11070233
State	Published - 2021

Bibliographical note

Publisher Copyright:
© 2021 by the author. Licensee MDPI, Basel, Switzerland.

Keywords

Aptamer
Aptasensor
One-site binding
Surface plasmon resonance
Two-site binding

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10.3390/bios11070233

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abstract = "Surface plasmon resonance (SPR) can track molecular interactions in real time, and is a powerful as well as widely used biological and chemical sensing technique. Among the different SPR-based sensing applications, aptamer-based SPR biosensors have attracted significant attention because of their simplicity, feasibility, and low cost for target detection. Continuous developments in SPR aptasensing research have led to the emergence of abundant technical and design concepts. To understand the recent advances in SPR for biosensing, this paper reviews SPR-based research from the last seven years based on different sensing-type strategies and sub-directions. The characteristics of various SPR-based applications are introduced. We hope that this review will guide the development of SPR aptamer sensors for healthcare.",

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AB - Surface plasmon resonance (SPR) can track molecular interactions in real time, and is a powerful as well as widely used biological and chemical sensing technique. Among the different SPR-based sensing applications, aptamer-based SPR biosensors have attracted significant attention because of their simplicity, feasibility, and low cost for target detection. Continuous developments in SPR aptasensing research have led to the emergence of abundant technical and design concepts. To understand the recent advances in SPR for biosensing, this paper reviews SPR-based research from the last seven years based on different sensing-type strategies and sub-directions. The characteristics of various SPR-based applications are introduced. We hope that this review will guide the development of SPR aptamer sensors for healthcare.

KW - Aptamer

KW - Aptasensor

KW - One-site binding

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KW - Two-site binding

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Recent advancements in aptamer-based surface plasmon resonance biosensing strategies

Abstract

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Keywords

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