Recurrence of idiopathic sudden sensorineural hearing loss: A retrospective cohort study

Che Ming Wu, Kuan Ji Lee, Shih Lun Chang, Shih Feng Weng, Yung Song Lin*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

16 Scopus citations

Abstract

Objective: To explore the recurrence rate of idiopathic sudden sensorineural hearing loss (ISSNHL).

Design: Using the Taiwan Longitudinal Health Insurance Database, we compared in a retrospective cohort study 45,715 patients with ISSNHL between January 2001 and December 2006 with 45,715 age-, gender-, and comorbidity-matched controls without ISSNHL. We followed each patient from 180 days after the initial diagnosis until the end of 2009 and evaluated the incidence of ISSNHL for 3 years minimum.

Results: The cumulative incidence of ISSNHL recurrence was 4.99%. Cox proportional hazard regressions showed that the 50-to 64-year-old age group had a higher adjusted hazard ratio (1.59; 95% confidence interval: 1.40-1.81) than did the 0-to 34-year-old age group. Different comorbidities did not significantly affect the incidence of ISSNHL relapse.

Conclusions: The risk of an ISSNHL relapse in patients with a history of ISSNHL was higher than was the risk of a first occurrence of ISSNHL in the Controls. We suggest that physicians counsel patients with a history of ISSNHL to seek medical attention if they have hearing impairments because they may also have a high risk of an ISSNHL relapse.

Evidence Level: 2B.

Original languageEnglish
Pages (from-to)1736-1741
Number of pages6
JournalOtology and Neurotology
Volume35
Issue number10
DOIs
StatePublished - 10 12 2014

Bibliographical note

Publisher Copyright:
© 2014, Otology & Neurotology, Inc.

Keywords

  • Chronic renal disease
  • Diabetes
  • Hypercholesterolemia
  • Hypertension
  • Idiopathic sudden sensorineural hearing loss
  • Stroke

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