Regioselective fluorination in synthesis of deoxyfluoro quercitols from d-(-)-quinic acid

Tzenge Lien Shih; Wen Yu Liao; Wen Chun Yen

doi:10.1016/j.tet.2014.11.001

Regioselective fluorination in synthesis of deoxyfluoro quercitols from d-(-)-quinic acid

Tzenge Lien Shih^*
, Wen Yu Liao
, Wen Chun Yen

^*Corresponding author for this work

Tamkang University

Research output: Contribution to journal › Journal Article › peer-review

1 Scopus citations

Abstract

A facile synthesis of six new deoxyfluoro querciotls from d-(-)-quinic acid is described. The key steps involve the regioselective fluorination as well as highly stereoselective dihydroxylation. These synthetic deoxyfluoro quercitols are considered as potential glycosidase inhibitors.

Original language	English
Pages (from-to)	9621-9627
Number of pages	7
Journal	Tetrahedron
Volume	70
Issue number	51
DOIs	https://doi.org/10.1016/j.tet.2014.11.001
State	Published - 23 12 2014
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Ltd.

Keywords

Deoxyfluoro quercitols
Fluorination
Glycosidase inhibitors
Regioselective fluorination
d-(-)-Quinic acid

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10.1016/j.tet.2014.11.001

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title = "Regioselective fluorination in synthesis of deoxyfluoro quercitols from d-(-)-quinic acid",

abstract = "A facile synthesis of six new deoxyfluoro querciotls from d-(-)-quinic acid is described. The key steps involve the regioselective fluorination as well as highly stereoselective dihydroxylation. These synthetic deoxyfluoro quercitols are considered as potential glycosidase inhibitors.",

keywords = "Deoxyfluoro quercitols, Fluorination, Glycosidase inhibitors, Regioselective fluorination, d-(-)-Quinic acid",

author = "Shih, \{Tzenge Lien\} and Liao, \{Wen Yu\} and Yen, \{Wen Chun\}",

note = "Publisher Copyright: {\textcopyright} 2014 Elsevier Ltd.",

year = "2014",

month = dec,

day = "23",

doi = "10.1016/j.tet.2014.11.001",

language = "英语",

volume = "70",

pages = "9621--9627",

journal = "Tetrahedron",

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number = "51",

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TY - JOUR

T1 - Regioselective fluorination in synthesis of deoxyfluoro quercitols from d-(-)-quinic acid

AU - Shih, Tzenge Lien

AU - Liao, Wen Yu

AU - Yen, Wen Chun

PY - 2014/12/23

Y1 - 2014/12/23

N2 - A facile synthesis of six new deoxyfluoro querciotls from d-(-)-quinic acid is described. The key steps involve the regioselective fluorination as well as highly stereoselective dihydroxylation. These synthetic deoxyfluoro quercitols are considered as potential glycosidase inhibitors.

AB - A facile synthesis of six new deoxyfluoro querciotls from d-(-)-quinic acid is described. The key steps involve the regioselective fluorination as well as highly stereoselective dihydroxylation. These synthetic deoxyfluoro quercitols are considered as potential glycosidase inhibitors.

KW - Deoxyfluoro quercitols

KW - Fluorination

KW - Glycosidase inhibitors

KW - Regioselective fluorination

KW - d-(-)-Quinic acid

UR - https://www.scopus.com/pages/publications/84911886342

U2 - 10.1016/j.tet.2014.11.001

DO - 10.1016/j.tet.2014.11.001

M3 - 文章

AN - SCOPUS:84911886342

SN - 0040-4020

VL - 70

SP - 9621

EP - 9627

JO - Tetrahedron

JF - Tetrahedron

IS - 51

ER -

Regioselective fluorination in synthesis of deoxyfluoro quercitols from d-(-)-quinic acid

Abstract

Bibliographical note

Keywords

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