Residual Gastric Volume after Bowel Preparation with Polyethylene Glycol for Elective Colonoscopy

Chi Liang Cheng*, Nai Jen Liu, Jui Hsiang Tang, Yen Lin Kuo, Cheng Hui Lin, Yi Ning Tsui, Bai Ping Lee, Yun Chiu Tai, Ming Yao Su, Cheng Tang Chiu

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

11 Scopus citations


Goal: To examine the residual gastric volume (RGV) in colonoscopy after bowel preparations with 3-L polyethylene glycol (PEG). Background: Obstacles to high-volume bowel preparation by anesthesia providers resulting from concerns over aspiration risk are common during colonoscopy. Study: Prospective measurements of RGV were performed in patients undergoing esophagogastroduodenoscopy (EGD) and morning colonoscopy with split-dose PEG preparation, patients undergoing EGD and afternoon colonoscopy with same-day PEG preparation, and patients undergoing EGD alone under moderate conscious sedation. Colonoscopy patients were allowed to ingest clear liquids until 2 hours before the procedure. Patients undergoing EGD alone were instructed to eat/drink nothing after midnight. Results: There were 860 evaluated patients, including 330 in the split-dose preparation group, 100 in the same-day preparation group, and 430 in the EGD-only group. Baseline demographics and disease/medication factors were similar. The mean RGV in patients receiving the same-day preparation (35.4 mL or 0.56 mL/kg) was significantly higher than that in patients receiving the split-dose preparation (28.5 mL or 0.45 mL/kg) and in patients undergoing EGD alone (22.8 mL or 0.36 mL/kg) (P=0.023 and P<0.0001, respectively). Within the bowel-preparation groups, patients with fasting times of 2 to 3 hours had similar RGV compared with patients who had fasting times >3 hours. The shape of the distribution and the range of RGV among the 3 study groups were similar. No aspiration occurred in any group. Conclusions: PEG bowel preparations increase RGV mildly, but seem to have no clinical significance. These results support the current fasting guidelines for colonoscopy.

Original languageEnglish
Pages (from-to)331-338
Number of pages8
JournalJournal of Clinical Gastroenterology
Issue number4
StatePublished - 2017

Bibliographical note

Publisher Copyright:
© 2016 Wolters Kluwer Health, Inc. All rights reserved.


  • aspiration
  • colonoscopy
  • conscious sedation
  • polyethylene glycol
  • residual gastric volume


Dive into the research topics of 'Residual Gastric Volume after Bowel Preparation with Polyethylene Glycol for Elective Colonoscopy'. Together they form a unique fingerprint.

Cite this