Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

Toshifumi Miyazawa*, Kazuki Onishi, Takashi Murashima, Takashi Yamada, Shau Wei Tsai

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

16 Scopus citations

Abstract

Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E = >200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.

Original languageEnglish
Pages (from-to)2569-2573
Number of pages5
JournalTetrahedron Asymmetry
Volume16
Issue number15
DOIs
StatePublished - 01 08 2005
Externally publishedYes

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